Juvenile localized scleroderma

被引：0

作者：

Strauss, Timmy ^{[1
,2
]}

Guenther, Claudia ^{[2
,3
]}

Brueck, Normi ^{[1
,2
]}

机构：

[1] Tech Univ Dresden, Klin & Poliklin Kinder & Jugendmed, Med Fak, Fetscherstr 74, D-01307 Dresden, Germany

[2] Tech Univ Dresden, Univ Klinikum Carl Gustav Carus, Fetscherstr 74, D-01307 Dresden, Germany

[3] Tech Univ Dresden, Klin & Poliklin Dermatol, Med Fak, Dresden, Germany

来源：

DERMATOLOGIE | 2024年 / 75卷 / 03期

关键词：

Morphea; Juvenile localized scleroderma; Sequelae; Progression; Clinical practice guidelines; TOPICAL TACROLIMUS 0.1-PERCENT; MORPHEA; CORTICOSTEROIDS; METHOTREXATE; CHILDREN; PATHOGENESIS; DEEP;

D O I：

10.1007/s00105-023-05293-5

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Juvenile scleroderma, often referred to as juvenile localized scleroderma or "morphea", is a rare inflammatory disease of the skin and skin-related structures, accompanied by local sclerosis and tissue fibrosis. Depending on the clinical manifestation, four different subtypes can be defined: limited, generalized, linear, and mixed. To prevent possible sequelae of the disease, the diagnosis should be made as early as possible and therapy should be initiated at specialized centers in multiprofessional pediatric and dermatologic collaboration. In this review, we present the main clinical, laboratory, and therapeutic characteristics of juvenile localized scleroderma and summarize recommendations.

引用

页码：208 / 213

页数：6

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