Manifestation of Pancytopenia Associated with COVID-19 as Paroxysmal Nocturnal Hemoglobinuria (PNH) and Aplastic Anemia (AA)

被引：1

作者：

Aguilar, Jeff Justin ^{[1
]}

Dhillon, Vikram ^{[2
]}

Balasubramanian, Suresh ^{[2
]}

机构：

[1] Wayne State Univ, Sch Med, Detroit, MI 48201 USA

[2] Wayne State Univ, Karmanos Canc Inst, Dept Oncol, Detroit, MI 48201 USA

来源：

HEMATOLOGY REPORTS | 2024年 / 16卷 / 01期

关键词：

paroxysmal nocturnal hemoglobinuria; aplastic anemia; SARS-CoV-2;

D O I：

10.3390/hematolrep16010005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report two cases of pancytopenia in patients after recovering from a mild COVID-19, now presenting as paroxysmal nocturnal hemoglobinuria (PNH) and aplastic anemia. These cases illustrate a common pathway whereby a viral trigger causes the clonal expansion of a hematological disorder. Although the association of both cases with COVID-19 is temporal and COVID-19 may be an incidental diagnosis, the growing evidence related to the hematological effects of SARS-CoV-2 infection highlights the need for further investigation into the hematological consequences of COVID-19, particularly in the post-pandemic era.

引用

页码：42 / 49

页数：8

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