Utilizing as-synthesized Reduced Graphene Oxide Decorated with Mn1-xZnxFe2-yCuyO4 Doped Magnetic Nanoparticles for Efficient Electrochemical Sensing of Paracetamol

被引:3
作者
Rahman, Mehboob Ur [1 ,2 ]
Khan, Rafaqat Ali [1 ]
Khan, Asad Muhammad [1 ]
Sreearunothai, Paiboon [2 ]
Shah, Faheem [1 ,3 ]
Muhammad, Haji [4 ]
Shaikh, Ahson Jabbar [1 ]
Ismail, Bushra [1 ]
Noor, Umar [2 ]
机构
[1] COMSATS Univ Islamabad, Dept Chem, Abbottabad Campus, Abbottabad 22060, Khyber Pakhtunk, Pakistan
[2] Thammasat Univ, Sirindhorn Int Inst Technol SIIT, Funct Adv Mat Engn Res Ctr FAME, Sch Integrated Sci & Innovat ISI, Thammasat, Thailand
[3] King Faisal Univ, Sch Sci, Dept Chem, Al Hufuf 31982, Eastern Provinc, Saudi Arabia
[4] Fed Urdu Univ Arts Sci & Technol, Fac Sci, Dept Chem, Gulshan E Iqbal Campus, Karachi 75300, Pakistan
关键词
sensor; reduced graphene oxide; limit of detection; cyclic voltammetry; ferrites; limit of quantification; CARBON-PASTE ELECTRODE; FERRITE NANOPARTICLES; SENSOR; ZN; METAL; NI;
D O I
10.1149/1945-7111/ad3058
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
A highly sensitive sensor for paracetamol detection based on the copper and zinc doped manganese ferrite/reduced graphene oxide modified glassy carbon electrode (Mn1-xZnxFe2-yCuyO4/rGO/GCE) is ameliorated. X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectrometry (FTIR), zeta-sizer, cyclic voltammetry, and electrochemical impedance spectroscopy are used to examine the structural, morphological, electroanalytical capability of the designed sensor. Results are correlated systematically for the copper/zinc doped manganese ferrite/reduced graphene oxide modified glassy carbon electrode and it is observed that the sensor exhibits two linear ranges as 5-9 mu mol l(-1) and 9-200 mu mol l(-1) under the optimized conditions. Doped composite-modified GCE demonstrates an exceptional limit of detection (LOD) (0.04 mu mol l(-1)) and the limit of quantification (LOQ) (0.15 mu mol l(-1)). The possible effect of structurally similar drugs on the anodic current response of paracetamol is evaluated. By analyzing the current generation of the actual pharmaceutical samples, the practical application of the manufactured sensor is assessed. Promising results demonstrated by modified GC electrode affirm its excellent analytical performance for the sensing of paracetamol with trace-level detection and high sensitivity.
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页数:11
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