Chicago Classification v4.0 Stratifies Acid Burden and Abnormal Impedance-pH Variables Better Than Chicago Classification v3.0 Chicago Classification v4.0 and GERD

被引：4

作者：

Ribolsi, Mentore ^{[1
]}

Marchetti, Lorenzo ^{[1
]}

Savarino, Edoardo ^{[2
]}

Gyawali, C. Prakash ^{[3
]}

Cicala, Michele ^{[1
]}

机构：

[1] Campus Bio Med Univ Rome, Dept Digest Dis, Rome, Italy

[2] Univ Padua, Dept Surg Oncol & Gastroenterol, Gastroenterol Unit, Padua, Italy

[3] Washington Univ, Sch Med, Div Gastroenterol, St Louis, MO USA

来源：

AMERICAN JOURNAL OF GASTROENTEROLOGY | 2024年 / 119卷 / 01期

关键词：

pH-impedance; high-resolution manometry; Chicago Classification v3.0; Chicago Classification v4.0; GERD; ESOPHAGEAL MOTILITY DISORDERS; REFLUX;

D O I：

10.14309/ajg.0000000000002491

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

INTRODUCTION: Gastroesophageal reflux disease (GERD) severity increases with esophageal body hypomotility, but the impact of Chicago Classification (CC) v4.0 criteria on GERD diagnosis is incompletely understood.METHODS: In patients with GERD evaluated with high-resolution manometry and pH-impedance monitoring, CCv3.0 and CCv4.0 diagnoses were compared.RESULTS: In 247 patients, hypomotility diagnosis decreased from 45.3% (CCv3.0) to 30.0% (CCv4.0, P < 0.001). In contrast, within patients with ineffective esophageal motility, proportions with pathological acid exposure increased from 38% (CCv3.0) to 88% (CCv4.0); baseline impedance and esophageal clearance demonstrated similar findings (P < 0.05 for each comparison).DISCUSSION: CCv4.0 hypomotility criteria are more specific in supporting GERD evidence compared with CCv3.0.

引用

页码：206 / 209

页数：4

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