Comparison of clinical outcomes in patients with acute ischemic stroke who underwent endovascular treatment using different perfusion modalities: a real-world multicenter study

被引：2

作者：

Gao, Jiali ^{[1
]}

Jing, Zhen ^{[1
]}

Huang, Shengming ^{[1
]}

Yang, Jiajie ^{[1
]}

Guan, Min ^{[1
]}

Zhang, Shijun ^{[2
]}

Li, Hao ^{[3
]}

Li, Yongxin ^{[4
]}

Lu, Kui ^{[5
]}

Yang, Ming ^{[6
]}

Huang, Li'an ^{[1
]}

机构：

[1] Jinan Univ, Clin Neurosci Inst, Dept Neurol, Affiliated Hosp 1, Guangzhou, Peoples R China

[2] Guangzhou Med Univ, Dept Neurol, Affiliated Hosp 4, Guangzhou, Peoples R China

[3] Maoming Peoples Hosp, Dept Neurol, Maoming, Peoples R China

[4] Southern Med Univ, Dept Neurol, Shunde Hosp, Foshan, Peoples R China

[5] Zhongshan Peoples Hosp, Dept Neurol, Zhongshan, Peoples R China

[6] Neuroblem Ltd Co, Shanghai, Peoples R China

来源：

FRONTIERS IN NEUROLOGY | 2023年 / 14卷

关键词：

computed tomography perfusion; arterial spin labeling; stroke; endovascular treatment; imaging; THROMBECTOMY; THERAPY; GUIDELINES; MANAGEMENT; SELECTION; TRIAL;

D O I：

10.3389/fneur.2023.1275715

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: Advanced perfusion modalities are increasingly popular for various diseases. However, few studies have focused on contrasting perfusion patterns. Objective: This study aimed to compare the time efficiency and clinical outcomes of patients with acute ischemic stroke (AIS) who underwent endovascular treatment (EVT) before one-stop arterial spin labeling (ASL) and computed tomography perfusion (CTP) protocols. Methods: This study retrospectively included 326 patients with AIS who had accepted EVT within 24 h of onset from four comprehensive stroke centers between October 2017 and September 2022. After 1:1 matching of the propensity scores, 202 patients were separated into two groups: the ASL group (n = 101) and the CTP group (n = 101). Results: Functional independence at 90 days (modified Rankin Scale [mRS] 0-2; p = 0.574), onset-to-puncture time (p = 0.231), door-to-puncture time (p = 0.136), and door-to-perfusion time (p = 0.646) were not significantly different between the two groups. The proportion of EVT complications (31.7% in the ASL group vs. 14.9% in the CTP group, p = 0.005) and symptomatic intracranial hemorrhage (sICH) at 24 h (23.8% in the ASL group vs. 9.9% in the CTP group, p = 0.008) in the CTP group were lower than the ASL group. The ischemic core volume was a common predictor of favorable outcomes in both ASL (p < 0.001) and CTP (p < 0.001) groups. Conclusion: There were no significant differences in time efficiency and efficacy outcomes between the two groups of patients receiving one-stop ASL and CTP. The proportion of sICH at 24 h and EVT complications of patients in the CTP group was lower than the ASL group. The ischemic core volume was an independent predictor for favorable outcomes.

引用

页数：9

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