Post-Cardiac Arrest Syndrome

被引：14

作者：

Penketh, James ^{[1
]}

Nolan, Jerry P. ^{[1
,2
]}

机构：

[1] Royal United Hosp, Intens Care unit, Bath, England

[2] Univ Warwick, Warwick Clin Trials Unit, Coventry, England

来源：

JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY | 2023年 / 35卷 / 03期

关键词：

post-cardiac arrest syndrome; hypoxic-ischemic brain injury; hyperoxia; temperature control; prognostication; TARGETED TEMPERATURE MANAGEMENT; PROGNOSTIC-SIGNIFICANCE; CARE; HYPOTHERMIA; DEATH; CARDIOPULMONARY; RESUSCITATION; METAANALYSIS; MODE;

D O I：

10.1097/ANA.0000000000000921

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Post-cardiac arrest syndrome (PCAS) is a multi component entity affecting many who survive an initial period of resuscitation following cardiac arrest. This focussed review explores some of the strategies for mitigating the effects of PCAS following the return of spontaneous circulation. We consider the current evidence for controlled oxygenation, strategies for blood pressure targets, the timing of coronary reperfusion, and the evidence for temperature control and treatment of seizures. Despite several large trials investigating specific strategies to improve outcomes after cardiac arrest, many questions remain unanswered. Results of some studies suggest that interventions may benefit specific subgroups of cardiac arrest patients, but the optimal timing and duration of many interventions remain unknown. The role of intracranial pressure monitoring has been the subject of only a few studies, and its benefits remain unclear. Research aimed at improving the management of PCAS is ongoing.

引用

页码：260 / 264

页数：5

共 45 条

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