Neurosyphilis with oral-facial-lingual dyskinesia: A case report

被引:0
作者
Liang, Yingfang [1 ]
Li, Bixun [1 ]
Ou, Danyan [1 ]
Li, Guoliang [2 ]
Zeng, Hao [3 ]
机构
[1] Guangxi Med Univ, Canc Hosp, Dept Comprehens Internal Med, Nanning 530022, Guangxi, Peoples R China
[2] Cent South Univ, Xiangya Hosp, Dept Neurol, Changsha 410008, Hunan, Peoples R China
[3] Guangxi Med Univ, Affiliated Hosp 1, Dept Spine & Osteopathy Surg, Nanning 530022, Guangxi, Peoples R China
基金
中国国家自然科学基金;
关键词
syphilis; dyskinesia; rhythmic orofacial involuntary movements; neurosyphilis; orofacial;
D O I
10.3892/etm.2023.12219
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The present study describes the case of a 52-year-old male patient who presented with subacute onset dysarthria and oral-facial-lingual dyskinesia, with normal blood glucose and acanthocyte levels, and no history of drug use. The patient tested negative for autoimmune encephalitis-related antibodies and paraneoplastic-related antibodies. The level of cerebrospinal fluid (CSF) protein was slightly elevated, and the Treponema pallidum hemagglutination assay and rapid plasma reagin test were positive in both serum and CSF samples. After 1 month of treatment with doxycycline, the patient's oral-facial-lingual dyskinesia was significantly improved, suggesting the diagnosis of neurosyphilis.
引用
收藏
页数:4
相关论文
共 10 条
[1]   CT and MRI rating of white matter lesions [J].
Fazekas, F ;
Barkhof, F ;
Wahlund, LO ;
Pantoni, L ;
Erkinjuntti, T ;
Scheltens, P ;
Schmidt, R .
CEREBROVASCULAR DISEASES, 2002, 13 :31-36
[2]   Management of Adult Syphilis: Key Questions to Inform the 2015 Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines [J].
Ghanem, Khalil G. .
CLINICAL INFECTIOUS DISEASES, 2015, 61 :S818-S836
[3]   German guidelines on the diagnosis and treatment of neurosyphilis [J].
Klein, Matthias ;
Angstwurm, Klemens ;
Esser, Stefan ;
Hahn, Kathrin ;
Maschke, Matthias ;
Scheithauer, Simone ;
Schoefer, Helmut ;
Sturzenegger, Matthias ;
Wildemann, Brigitte ;
Weber, Joerg .
NEUROLOGICAL RESEARCH AND PRACTICE, 2020, 2 (01)
[4]  
Lenka A, 2017, TREMOR OTHER HYPERK, V7, DOI 10.7916/D8000DKM
[5]   Neurosyphilis orofacial dyskinesia: The candy sign [J].
Martinelli, Paolo ;
Rizzo, Giovanni ;
Scaglione, Cesa ;
Capellari, Sabina .
MOVEMENT DISORDERS, 2013, 28 (02) :246-247
[6]  
Marto JP, 2017, NEUROLOGY, V88, pE35, DOI 10.1212/WNL.0000000000003544
[7]   A case of neurosyphilis presenting with myoclonus, cerebellar ataxia, and speech disturbance [J].
Shah, Binit B. ;
Lang, Anthony E. .
MOVEMENT DISORDERS, 2012, 27 (06) :794-794
[8]   Acquired neurosyphilis presenting as movement disorders [J].
Shah, Binit B. ;
Lang, Anthony E. .
MOVEMENT DISORDERS, 2012, 27 (06) :690-695
[9]   Case Report: Not All Neurological Symptoms Respond Well to Penicillin in Patients With Neurosyphilis [J].
Wang, Xiaoli ;
Mu, Pengying ;
Zhang, Wenjuan ;
Liu, Yonghong .
FRONTIERS IN NEUROLOGY, 2022, 12
[10]   Factors that influence Tolosa-Hunt syndrome and the short-term response to steroid pulse treatment [J].
Zhang, Xingwen ;
Zhang, Wei ;
Liu, Ruozhuo ;
Dong, Zhao ;
Yu, Shengyuan .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2014, 341 (1-2) :13-16