Cryptococcal meningitis post-COVID-19 infection: Immunomodulation, a double-edged sword

被引：3

作者：

Abdessamad, Hilal W. ^{[1
,2
]}

Achkar, Michel ^{[2
,3
]}

Al Zoghbi, Amal ^{[2
,4
]}

Fleifel, Mohamad ^{[2
,3
]}

Ousta, Abdul Rahman ^{[2
,5
]}

Kassar, Ahmad ^{[2
,5
]}

Samaha, Nadia L. ^{[6
]}

Nemr, Rita ^{[2
,4
]}

Farra, Anna ^{[1
,2
]}

Mokhbat, Jacques E. ^{[1
,2
]}

Husni, Rola ^{[1
,2
,7
]}

机构：

[1] Lebanese Amer Univ, Sch Med, Infect Dis, Beirut, Lebanon

[2] Lebanese Amer Univ, Rizk Hosp, Med Ctr, Beirut, Lebanon

[3] Lebanese Amer Univ, Sch Med, Internal Med, Beirut, Lebanon

[4] Lebanese Amer Univ, Sch Med, Endocrinol, Beirut, Lebanon

[5] Lebanese Amer Univ, Sch Med, Beirut, Lebanon

[6] Georgetown Univ, Sch Med, Washington, DC USA

[7] Lebanese Amer Univ, Sch Med, Beirut, Lebanon

来源：

JOURNAL OF INFECTION IN DEVELOPING COUNTRIES | 2023年 / 17卷 / 05期

关键词：

cryptococcus; meningitis; immunomodulation; COVID-19; ESCHERICHIA-COLI MENINGITIS; CENTRAL DIABETES-INSIPIDUS; COMPLICATION; HYPOPITUITARISM; NEOFORMANS;

D O I：

10.3855/jidc.17170

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Cryptococcal meningitis is an opportunistic infection associated with altered immunity. Immunomodulatory agent use in severe coronavirus disease 2019 (COVID-19) may predispose such infections. Here, we present a 75-year-old male patient who presented with fever and altered general status after severe COVID-19 infection and developed cryptococcal meningitis. Opportunistic infection may arise from the use of immunomodulation in severe COVID-19, especially in the elderly population. This article describes the case and extensively reviews cryptococcal disease post-COVID-19 literature, highlighting the risk from immunosuppressive treatment.

引用

页码：623 / +

页数：10

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