Occurrence, ecology risk assessment and exposure evaluation of 19 anthelmintics in dust and soil from China

In order to fill the blank of domestic research on anthelmintics in dust and soil, 159 paired dust (including indoor and outdoor dust) and soil samples were collected nationwide. All 19 kinds of the anthelmintics were detected in the samples. The total concentration of the target substances in the outdoor dust, indoor dust and soil samples ranged from 1.83 to 1.30 x 103 ng/g, from 2.99 to 6.00 x 103 ng/g and from 0.23 to 8.03 x 102 ng/g, respectively. The total concentration of the 19 anthelmintics in northern China were significantly higher than those in southern China in the outdoor dust and soil samples. No significant correlation was found in the total concentration of anthelmintics between the indoor and outdoor dust because of strong human activities inter-ference, however, a significant correlation existed between the outdoor dust and soil samples and between the indoor dust and soil samples. High ecological risk was found at 35% and 28% of all the sampling sites to non -target organisms in the soil respectively for IVE and ABA, and merits further study. The daily anthelmintics intakes were evaluated via ingestion and dermal contact of soil and dust samples for both children and adults. Ingestion was the predominant way for anthelmintics exposure, and the anthelmintics in soil and dust did not pose a health threat to human health at present.