Prognosis and treatment outcomes for patients with stage IA triple-negative breast cancer

被引：10

作者：

Tarantino, Paolo ^{[1
,2
,3
,4
]}

Leone, Julieta ^{[5
]}

Vallejo, Carlos T. ^{[5
]}

Freedman, Rachel A. ^{[1
,2
,3
]}

Waks, Adrienne G. ^{[1
,2
,3
]}

Martinez-Saez, Olga ^{[1
,2
,6
,7
]}

Garrido-Castro, Ana ^{[1
,2
,3
]}

Lynce, Filipa ^{[1
,2
,3
]}

Tayob, Nabihah ^{[1
,3
]}

Lin, Nancy U. ^{[1
,2
,3
]}

Tolaney, Sara M. ^{[1
,2
,3
]}

Leone, Jose P. ^{[1
,2
,3
]}

机构：

[1] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02215 USA

[2] Dana Farber Brigham Canc Ctr, Breast Oncol Program, Boston, MA 02215 USA

[3] Harvard Med Sch, Boston, MA 02115 USA

[4] Univ Milan, Dept Oncol & Oncohematol, Milan, Italy

[5] Grp Oncol Cooperat Sur, Neuquen, Argentina

[6] Hosp Clin Barcelona, Med Oncol Dept, Barcelona, Spain

[7] August Pi i Sunyer Biomed Res Inst IDIBAPS, Translat Genom & Targeted Therapeut Solid Tumors, Barcelona, Spain

来源：

NPJ BREAST CANCER | 2024年 / 10卷 / 01期

关键词：

FEATURES; PATTERNS; WOMEN;

D O I：

10.1038/s41523-024-00634-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

To evaluate the role of chemotherapy in stage IA triple-negative breast cancer, we conducted a retrospective population-based study including 8601 patients. The use of chemotherapy significantly increased from 2010 to 2019 in patients with T1b and T1c tumors (p = 0.001 and p < 0.001, respectively). Receipt of chemotherapy was associated with improved breast cancer-specific survival (BCSS, adjusted hazard ratio = 0.70; p = 0.006), particularly in patients with T1c tumors (5-year BCSS 94.5% vs. 91.2%).

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页数：4

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