BackgroundPlacental cord drainage (PCD) after vaginal birth accelerates placental delivery by 2.85 minutes, but reduces blood loss by only 77 mL.AimsTo determine if PCD at elective caesarean section accelerates placental delivery, compared to delayed cord clamping (DCC).Materials and MethodsThis randomised controlled trial randomised 100 women undergoing elective caesarean sections to receive either PCD for 60 sec after birth, or DCC for 60 sec. The primary outcome was time from birth until placental delivery. Secondary outcomes included estimated blood loss (EBL), postoperative haemoglobin drop, rates of postpartum haemorrhage (PPH), manual removal of placenta and blood transfusion.ResultsThere was no significant difference in timing of placental delivery (PCD 122 sec vs DCC 123.5 sec, P = 0.717). There were no significant differences in EBL (PCD 425 mL vs DCC 400 mL, P = 0.858), postoperative haemoglobin drop (PCD 12 g/L vs DCC 15 g/L, P = 0.297), PPH rate (PCD 45.8% vs DCC 44.4%, P = 0.893, relative risk (RR) 1.03, 95% confidence interval (CI) 0.66-1.62), manual removal rate (PCD 2.1% vs DCC 4.4%, P = 0.609, RR 0.47, 95% CI 0.04-4.99) or transfusion rate (PCD 4.2% vs DCC 0%, P = 0.495).ConclusionsPCD did not accelerate placental delivery at caesarean compared with DCC. Given that both PCD and DCC groups had faster placental deliveries than quoted in the literature at caesarean (200 sec), it could be postulated that DCC is mimicking the effect of PCD through passive transfusion to the neonate. This supports routine use of DCC at elective caesarean section.
机构:
Hull Royal Infirm, Hull & E Yorkshire Women & Childrens Hosp, Dept Obstet & Gynaecol, Kingston Upon Hull HU3 2JZ, East Yorkshire, EnglandHull Royal Infirm, Hull & E Yorkshire Women & Childrens Hosp, Dept Obstet & Gynaecol, Kingston Upon Hull HU3 2JZ, East Yorkshire, England
Navaneethakrishnan, R.
Anderson, A.
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Hull Royal Infirm, Dept Immunol, Kingston Upon Hull HU3 2JZ, East Yorkshire, EnglandHull Royal Infirm, Hull & E Yorkshire Women & Childrens Hosp, Dept Obstet & Gynaecol, Kingston Upon Hull HU3 2JZ, East Yorkshire, England
Anderson, A.
Holding, S.
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Hull Royal Infirm, Dept Immunol, Kingston Upon Hull HU3 2JZ, East Yorkshire, EnglandHull Royal Infirm, Hull & E Yorkshire Women & Childrens Hosp, Dept Obstet & Gynaecol, Kingston Upon Hull HU3 2JZ, East Yorkshire, England
Holding, S.
Atkinson, C.
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Hull Royal Infirm, Hull & E Yorkshire Women & Childrens Hosp, Dept Obstet & Gynaecol, Kingston Upon Hull HU3 2JZ, East Yorkshire, EnglandHull Royal Infirm, Hull & E Yorkshire Women & Childrens Hosp, Dept Obstet & Gynaecol, Kingston Upon Hull HU3 2JZ, East Yorkshire, England
Atkinson, C.
Lindow, S. W.
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Hull Royal Infirm, Hull & E Yorkshire Women & Childrens Hosp, Dept Obstet & Gynaecol, Kingston Upon Hull HU3 2JZ, East Yorkshire, EnglandHull Royal Infirm, Hull & E Yorkshire Women & Childrens Hosp, Dept Obstet & Gynaecol, Kingston Upon Hull HU3 2JZ, East Yorkshire, England
机构:
All India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, IndiaAll India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, India
Sahoo, Tanushree
Thukral, Anu
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All India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, IndiaAll India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, India
Thukral, Anu
Sankar, M. Jeeva
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All India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, IndiaAll India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, India
Sankar, M. Jeeva
Gupta, Saurabh Kumar
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All India Inst Med Sci, Dept Cardiol, Div Pediat Cardiol, New Delhi, IndiaAll India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, India
Gupta, Saurabh Kumar
Agarwal, Ramesh
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All India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, IndiaAll India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, India
Agarwal, Ramesh
Deorari, Ashok K.
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All India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, IndiaAll India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, India
Deorari, Ashok K.
Paul, Vinod K.
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All India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, IndiaAll India Inst Med Sci, Dept Pediat, Div Neonatol, New Delhi 110029, India
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Beilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Tel Aviv Univ, Fac Med, Tel Aviv, IsraelBeilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Hendin, Natav
Grosvald, Michal
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Beilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Tel Aviv Univ, Fac Med, Tel Aviv, IsraelBeilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Grosvald, Michal
Shemesh, Ilana
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Beilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Tel Aviv Univ, Fac Med, Tel Aviv, IsraelBeilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Shemesh, Ilana
Leonenko, Marina
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Beilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Tel Aviv Univ, Fac Med, Tel Aviv, IsraelBeilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Leonenko, Marina
Jbara, Mursi
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Tel Aviv Univ, Fac Med, Tel Aviv, IsraelBeilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Jbara, Mursi
Segal, Kinneret
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Beilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Tel Aviv Univ, Fac Med, Tel Aviv, IsraelBeilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Segal, Kinneret
Geron, Yossi
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Beilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Tel Aviv Univ, Fac Med, Tel Aviv, IsraelBeilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Geron, Yossi
Borovich, Adi
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Beilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, IsraelBeilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Borovich, Adi
Chen, Rony
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Tel Aviv Univ, Fac Med, Tel Aviv, IsraelBeilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Chen, Rony
Hadar, Eran
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Beilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Tel Aviv Univ, Fac Med, Tel Aviv, IsraelBeilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Hadar, Eran
Walfisch, Asnat
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Beilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Tel Aviv Univ, Fac Med, Tel Aviv, IsraelBeilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Walfisch, Asnat
Houri, Ohad
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Beilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel
Tel Aviv Univ, Fac Med, Tel Aviv, IsraelBeilinson Med Ctr, Helen Schneider Hosp Women, Rabin Med Ctr, Petah Tiqwa, Israel