Mandibular glands secrete 24-methylenecholesterol into honey bee (Apis mellifera) food jelly

被引：3
作者：
Buttstedt, Anja [1 ]
Pirk, Christian W. W. [1 ]
Yusuf, Abdullahi A. [1 ]
机构：
[1] Univ Pretoria, Dept Zool & Entomol, Social Insects Res Grp, Private Bag X20, ZA-0028 Pretoria, South Africa
来源：
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY | 2023年 / 161卷
关键词：
Mandibular glands; Hypopharyngeal glands; 10-HDA; MRJP1; Sterol; 24-Methylenecholesterol; 10-HYDROXY-DELTA2-DECENOIC ACID; HYPOPHARYNGEAL GLANDS; HYMENOPTERA APIDAE; STEROL UTILIZATION; SOCIAL PARASITISM; SYNTHETIC DIET; QUEEN LARVAE; ROYAL; COMPONENTS; PROTEINS;
D O I：
10.1016/j.ibmb.2023.104011
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Honey bee (Apis mellifera) workers feed their larvae with food jelly that is secreted by specialized glands in their heads - the hypopharyngeal and the mandibular glands. Food jelly contains all the nutrients the larvae need to develop into adult honey bees, including essential dietary sterols. The main sterol in food jelly, 24-methylenecho-lesterol (24MC), is pollen-derived and delivered in food jelly to the larvae in a complex with two proteins, major royal jelly protein 1 (MRJP1) and apisim. Whereas the proteins are synthesized in the hypopharyngeal glands, the sterol-secreting gland has not been identified. We here identified the mandibular glands as sterol-secreting gland for food jelly production by direct detection of the four main honey bee sterols (24MC, campesterol, beta-sitosterol and isofucosterol). Furthermore, 24MC seems to be specifically enriched in the mandibular glands, thereby ensuring that food jelly contains the amounts of 24MC necessary for complex formation with MRJP1 and apisimin.
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页数：9
相关论文
共 90 条
[1]   Novel Insight Into the Development and Function of Hypopharyngeal Glands in Honey Bees [J].
Ahmad, Saboor ;
Khan, Shahmshad Ahmed ;
Khan, Khalid Ali ;
Li, Jianke .
FRONTIERS IN PHYSIOLOGY, 2021, 11
[2]  
[Anonymous], 1792, Nouvelles observations sur les abeilles
[3]  
Aristotle, 1965, HIST ANIM
[4]   ISOLIERUNG VON 24-METHYLENCHOLESTERIN AUS KONIGINNEN UND ARBEITERINNEN DER HONIGBIENE (APISMELLIFICA L) [J].
BARBIER, M ;
SCHINDLER, O .
HELVETICA CHIMICA ACTA, 1959, 42 (06) :1998-2005
[5]   New Criterion for Evaluation of Honey: Quantification of Royal Jelly Protein Apalbumin 1 in Honey by ELISA [J].
Bilikova, Katarina ;
Simuth, Jozef .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2010, 58 (15) :8776-8781
[6]   10-HYDROXY-DELTA2-DECENOIC ACID, AN ANTIBIOTIC FOUND IN ROYAL JELLY [J].
BLUM, MS ;
NOVAK, AF ;
TABER, S .
SCIENCE, 1959, 130 (3373) :452-453
[7]  
BOCH R, 1967, Z VERGL PHYSIOL, V54, P1
[8]   SOME NEW COMPONENTS OF ROYAL JELLY [J].
BROWN, WH ;
FREURE, RJ ;
FELAUER, EE .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1961, 39 (05) :1086-&
[9]   UBER DEN WEISELZELLENFUTTERSAFT DER HONIGBIENE .1. ISOLIERUNG, KONSTITUTIONSERMITTLUNG UND VORKOMMEN DER 10-HYDROXY-DELTA-2-DECENSAURE [J].
BUTENANDT, A ;
REMBOLD, H .
HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, 1957, 308 (5-6) :284-289
[10]  
Butler C.G., 1958, Proceedings of the Royal Entomological Society of London A, V33, P7, DOI [10.1111/j.1365-3032.1958.tb00458x, DOI 10.1111/J.1365-3032.1958.TB00458X]
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