CROHN'S DISEASE PATIENTS WITH USTEKINUMAB-INDUCED REMISSION ARE CHARACTERIZED BY HIGH BASELINE IL23 RECEPTOR EXPRESSION IN THE LAMINA PROPRIA TH1 CELLS

被引：0
|
作者：
Onali, S. [1 ]
Di, Petrillo A. [1 ]
Favale, A. [1 ]
Carpineti, C. [1 ]
Cadoni, M. [1 ]
Loddo, E. [1 ]
Fantini, M. C. [1 ]
机构：
[1] Univ Cagliari, Med Sci & Publ Healt, Cagliari, Italy
来源：
DIGESTIVE AND LIVER DISEASE | 2023年 / 55卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
T.06.1
引用
收藏
页码：S159 / S159
页数：1
相关论文
共 50 条
  • [31] Th1-mediated intestinal inflammation in Crohn's disease may be induced by activation of lamina propria lymphocytes through synergistic stimulation of interleukin-12 and interleukin-18 without T cell receptor engagement
    Okazawa, A
    Kanai, T
    Watanabe, M
    Yamazaki, M
    Inoue, N
    Ikeda, M
    Kurimoto, M
    Ishii, H
    Hibi, T
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2002, 97 (12): : 3108 - 3117
  • [32] COMPLEX PERIANAL CROHN'S DISEASE - ASSOCIATED WITH STRICTURING & PENETRATING PHENOTYPE, IBD SEROLOGIES, GENETIC VARIATIONS, AND PATHOGEN-DRIVEN, TH1/TH2, AND IL-23 SIGNALING PATHWAYS
    Patel, Sanket
    Dube, Shishir
    Haritunians, Talin
    Yang, Shaohong
    Fleshner, Phillip
    Zaghiyan, Karen
    Gu, Phillip
    Bonthala, Nirupama
    Yarur, Andres
    Vasiliauskas, Eric A.
    Ziring, David
    Rabizadeh, Shervin
    Targan, Stephan
    Melmed, Gil
    Mcgovern, Dermot P. B.
    GASTROENTEROLOGY, 2023, 164 (06) : S438 - S438
  • [33] Interleukin-12 receptor B2, a crucial component in the IL-12 TH1 response is up-regulated in Crohn's disease.
    Parrello, T
    Monteleone, G
    Sebkova, L
    Monteleone, I
    Doldo, P
    Marasco, R
    Pugliano, F
    Cucchiara, S
    Luzza, F
    Pallone, F
    GASTROENTEROLOGY, 2000, 118 (04) : A351 - A351
  • [34] High lymphocyte DNA 6-thioguanine levels are associated with a decrease in the TH1 cytokine response in patients with Crohn's disease on azathioprine therapy
    Cuffari, C
    Li, D
    Bayless, TM
    GASTROENTEROLOGY, 2003, 124 (04) : A11 - A11
  • [35] beta-(1,3)-Glucan derived from Candida albicans induces inflammatory cytokines from macrophages and lamina propria mononuclear cells derived from patients with Crohn's disease
    Mori, Kiyoto
    Naganuma, Makoto
    Mizuno, Shinta
    Suzuki, Hiroaki
    Kitazume, Mina T.
    Shimamura, Katsuyoshi
    Chiba, Sayako
    Sugita, Akira
    Matsuoka, Katsuyoshi
    Hisamatsu, Tadakazu
    Kanai, Takanori
    INTESTINAL RESEARCH, 2018, 16 (03) : 384 - +
  • [36] Development of Th1CD4+T-cells via IL-12 p70 in Crohn's disease but lack of development of Th1 cells via IL-12 p40 in ulcerative colitis
    Noguchi, M
    Hiwatashi, N
    Ohara, T
    Toyota, T
    GASTROENTEROLOGY, 1999, 116 (04) : A786 - A786
  • [37] High-Fat Feeding Increases Recruitment of ZO-1+Ocldn+CD11c+ Dendritic Cells to the Lamina Propria and Accelerates Disease Onset in a Murine Model of Crohn's Disease-Like Ileitis
    Gruber, Lisa
    Haller, Dirk
    GASTROENTEROLOGY, 2012, 142 (05) : S907 - S907
  • [38] A truncated IL-12rβ1 receptor ameliorates chronic graft-versus-host disease-induced lupus nephritis by inhibiting Th1 and Th17 cells
    Wang, Chen
    Guo, Wei
    Cai, Di
    Wang, Xin
    Yu, Dongmei
    Gao, Xiangdong
    Yao, Wenbing
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2015, 29 (02) : 544 - 551
  • [39] Mycobacterium bovis BCG-induced Th1 type CD4(+) suppressor T cells act by suppressing IL-2 production and IL-2 receptor expression
    Mustafa, AS
    NUTRITION, 1995, 11 (05) : 692 - 694
  • [40] Expression of Programmed Death-Ligand 1 by Human Colonic CD90+ Stromal Cells Differs Betweem Ulcerative Colitis and Crohn's Disease and Determines Their Capacity to Suppress Th1 Cells
    Beswick, Ellen J.
    Grim, Carl
    Singh, Abinav
    Aguirre, Jose E.
    Tafoya, Marissa
    Qiu, Suimin
    Rogler, Gerhard
    McKee, Rohini
    Samedi, Von
    Ma, Thomas Y.
    Reyes, Victor E.
    Powell, Don W.
    Pinchuk, Irina V.
    FRONTIERS IN IMMUNOLOGY, 2018, 9
12345