Heat transport across multi-layered skin tissue experiencing short-pulse laser irradiation: Case of temperature-dependent thermal physical parameters

Exactly tracing the heat transport within a multi-layered biological tissues exposed to a pulse laser irra-diation is the key issue for successful application of modern therapies. The purpose of this paper is to explore the heat transport within an irradiated biological tissue with multi-layered sub-structure and temperature-dependent physical properties. A non-linear model of bio-heat transfer involved variable physical properties with respected to the space and temperature has been firstly proposed on the ba-sis of dual-phase-lag model (DPL) of bio-heat transfer. A numerical procedure constructed on an explicit difference algorithm is then developed to trace the temperature history of each layer with temperature-dependent physical properties and associated thermal damage induced by a pulse laser. The parametric study of laser parameters, structure parameters of tissue and blood vessel, and variable thermal param-eters on thermal response has been performed. The results state that the heat transport has been in-hibited when considering temperature-dependent physical properties and a lower temperature would be predicted, which also would weaken the underlying thermal damage. (c) 2023 Elsevier Ltd. All rights reserved.