Lung cancer screening: Update, news and perspectives

被引:0
作者
Wang, Pascal [1 ]
Chapron, Jeanne [1 ]
Bennani, Souhail [3 ]
Revel, Marie-Pierre [3 ]
Wislez, Marie [1 ,2 ,3 ]
机构
[1] Univ Paris Cite, Hop Cochin, AP HP, Unite Oncol Thorac ,Serv Pneumol, F-75014 Paris, France
[2] Univ Paris, Sorbonne Univ, Ctr Rech Cordeliers, Team Inflammat Complement & Canc,INSERM, F-75006 Paris, France
[3] Univ Paris Cite, Hop Cochin, AP HP, Serv Radiol, F-75014 Paris, France
关键词
Screening; Lung cancer; CT scan; Lung nodule; Solitary pulmonary nodule; Tobacco smoking; DOSE CT; COMPUTED-TOMOGRAPHY; SPIRAL CT; TRIAL; MORTALITY; FEASIBILITY; ASSOCIATION; MULTICENTER; SURVIVAL; FRANCE;
D O I
10.1016/j.bulcan.2022.11.006
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Lung cancer is the leading cause of cancer death in France and worldwide (20 % of cancer deaths). This mortality is partly linked to an overrepresentation of metastatic stages at diagnosis (approximately 55 % of lung cancers at diagnosis). Low-dose chest CT in a target population to detect early forms accessible to radical treatment has been evaluated through multiple rando-mized trials (NLST, NELSON, MILD, DANTE. . .). These trials demonstrated a reduction in lung cancer specific mortality. The current problem is to integrate a CT screening policy CT at a national level, which should be both efficient and cost-effective, while presenting the least harms for the eligible population. Finally, it is necessary to optimize the participation of the eligible population and particularly in the most deprived areas and ensure the proper implementation of smoking cessation measures.
引用
收藏
页码:42 / 54
页数:13
相关论文
共 66 条
  • [1] Lung Cancer Incidence and Mortality with Extended Follow-up in the National Lung Screening Trial
    Aberle, Denise R.
    Black, William C.
    Chiles, Caroline
    Church, Timothy R.
    Gareen, Ilana F.
    Gierada, David S.
    Mahon, Irene
    Miller, Eric A.
    Pinsky, Paul F.
    Sicks, JoRean D.
    [J]. JOURNAL OF THORACIC ONCOLOGY, 2019, 14 (10) : 1732 - 1742
  • [2] Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening
    Aberle, Denise R.
    Adams, Amanda M.
    Berg, Christine D.
    Black, William C.
    Clapp, Jonathan D.
    Fagerstrom, Richard M.
    Gareen, Ilana F.
    Gatsonis, Constantine
    Marcus, Pamela M.
    Sicks, JoRean D.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (05) : 395 - 409
  • [3] Performance of ultralow-dose CT with iterative reconstruction in lung cancer screening: limiting radiation exposure to the equivalent of conventional chest X-ray imaging
    Adrian, Huber
    Julia, Landau
    Ebner, Lukas
    Yanik, Butikofer
    Lars, Leidolt
    Barbara, Brela
    Michelle, May
    Johannes, Heverhagen
    Andreas, Christe
    [J]. EUROPEAN RADIOLOGY, 2016, 26 (10) : 3643 - 3652
  • [4] [Anonymous], ACAPULCO CONT CRCDC
  • [5] [Anonymous], CANC POUM CANC PLUS
  • [6] [Anonymous], UK NSC REC INTR TARG
  • [7] [Anonymous], DEP CANC POUM SCANN
  • [8] [Anonymous], PROP COUNC REC CR ST
  • [9] [Anonymous], COST EFF CT SCREEN N, DOI [10.1056/nejmoa1312547, DOI 10.1056/NEJMOA1312547]
  • [10] Lung cancer mortality reduction by LDCT screening-Results from the randomized German LUSI trial
    Becker, Nikolaus
    Motsch, Erna
    Trotter, Anke
    Heussel, Claus P.
    Dienemann, Hendrik
    Schnabel, Philipp A.
    Kauczor, Hans-Ulrich
    Maldonado, Sandra Gonzalez
    Miller, Anthony B.
    Kaaks, Rudolf
    Delorme, Stefan
    [J]. INTERNATIONAL JOURNAL OF CANCER, 2020, 146 (06) : 1503 - 1513