Synthesis and Antiviral Activity of Copolymers of Hydroxycinnamic Acid with N-Vinylamides

被引：2
|
作者：
Nesterova, N. A. [1 ]
Shtro, A. A. [2 ]
Panarin, E. F. [1 ]
机构：
[1] Russian Acad Sci, Inst Macromol Cpds, St Petersburg 199004, Russia
[2] Russian Minist Hlth, Smorodintsev Res Inst Influenza, St Petersburg 197376, Russia
来源：
DOKLADY CHEMISTRY | 2023年 / 513卷 / 02期
关键词：
coumarin; copolymers of hydroxycinnamic acid; N-vinylamides; antiviral activity; hydroxycinnamic acid hydrazides;
D O I：
10.1134/S0012500823600992
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Radical copolymerization of coumarin with N-vinylamides (N-vinylpyrrolidone, N-methyl-N-vinylacetamide, N-vinylformamide) has been used to prepare copolymers of various composition with variable molecular weights. Subsequent reactions in their polymer chains affords water-soluble copolymers of salts of hydroxycinnamic acid and its hydrazides. The synthesized copolymers of hydroxycinnamic acid salts and hydrazides with N-vinylamides have low cytotoxicity and demonstrate the pronounced antiviral activity against human respiratory syncytial virus (strain A2).
引用
收藏
页码：389 / 392
页数：4
相关论文
共 50 条
  • [1] Synthesis and Antiviral Activity of Copolymers of Hydroxycinnamic Acid with N-Vinylamides
    N. A. Nesterova
    A. A. Shtro
    E. F. Panarin
    Doklady Chemistry, 2023, 513 : 389 - 392
  • [2] Immunomodulating properties of homo- and copolymers of N-vinylamides
    Panarin E.F.
    Ivanova N.P.
    Belokhvostova A.T.
    Potapenkova L.S.
    Pharmaceutical Chemistry Journal, 2006, 40 (3) : 141 - 144
  • [3] Synthesis of copolymers of 2-O-methacryloyl-D-gluclose and N-vinylamides
    Panarin, EF
    Ershov, AY
    Ivanova, NP
    RUSSIAN JOURNAL OF APPLIED CHEMISTRY, 2000, 73 (12) : 2085 - 2088
  • [4] NEW METHOD FOR THE SYNTHESIS OF N-VINYLAMIDES
    SCHMITT, G
    EBERTZ, W
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1982, 21 (08): : 630 - 631
  • [5] Synthesis of polymers and copolymers based on N-vinylamides containing anthracene type luminescent groups
    Krakovyak, M.G.
    Lushchik, V.B.
    Anan'eva, T.D.
    Panarin, Ye.F.
    Solovskii, M.V.
    Gorbunova, O.P.
    Gavrilova, I.I.
    Kirsh, Yu.E.
    Pautov, V.D.
    Ramazanova, M.R.
    Anufrieva, Ye.V.
    Polymer science USSR, 1987, 29 (03): : 669 - 675
  • [6] Living Radical polymerization of N-Vinylamides
    Pu Hongting
    Cai Xiangyu
    Wan Decheng
    Yang Genjin
    PROGRESS IN CHEMISTRY, 2008, 20 (10) : 1572 - 1577
  • [7] N-VINYLAMIDES - SYNTHESIS, PHYSICOCHEMICAL PROPERTIES, SPECIFIC FEATURES OF RADICAL POLYMERIZATION
    KIRSH, YE
    VYSOKOMOLEKULYARNYE SOEDINENIYA SERIYA A & SERIYA B, 1993, 35 (02): : B98 - B114
  • [8] A silicon-assisted synthesis of (E)-β-haloenamides from N-vinylamides
    Szudkowska-Fratczak, Justyna
    Zaranek, Maciej
    Hreczycho, Grzegorz
    Kubicki, Maciej
    Grabarkiewicz, Tomasz
    Pawluc, Piotr
    APPLIED ORGANOMETALLIC CHEMISTRY, 2015, 29 (05) : 270 - 275
  • [9] Chromatographic Analytical Control and Purification of Water-Soluble Carboxylated Copolymers Based on N-Vinylamides
    Krasikov, V. D.
    Borisenko, M. S.
    Malakhova, I. I.
    Gorshkov, N., I
    Bezrukova, M. A.
    Solovskii, M., V
    JOURNAL OF ANALYTICAL CHEMISTRY, 2019, 74 (11) : 1122 - 1126
  • [10] ALKYLATION OF ACTIVE HYDROGEN COMPOUNDS BY N-VINYLAMIDES
    HICKNER, RA
    JUDD, CI
    BAKKE, WW
    JOURNAL OF ORGANIC CHEMISTRY, 1967, 32 (03): : 729 - &
12345