S100A4 inhibition targets fibrosis in SSc

被引:2
作者
Mchugh, Jessica
机构
[1] Nature Reviews Rheumatology,
关键词
D O I
10.1038/s41584-024-01080-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
New findings suggest that targeting the DAMP protein S100A4 could mitigate both inflammatory and fibrotic pathways in systemic sclerosis.
引用
收藏
页码:67 / 67
页数:1
相关论文
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[1]   Effect of Anti-S100A4 Monoclonal Antibody Treatment on Experimental Skin Fibrosis and Systemic Sclerosis-Specific Transcriptional Signatures in Human Skin [J].
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Gyoerfi, Andrea-Hermina ;
Tomcik, Michal ;
Tran-Manh, Cuong ;
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Kreuter, Alexander ;
Burmann, Sven-Niklas ;
Borchert, Signe Vedel ;
Hussain, Rizwan Iqbal ;
Hallen, Jonas ;
Klingelhoefer, Jorg ;
Kunz, Meik ;
Distler, Jorg H. W. .
ARTHRITIS & RHEUMATOLOGY, 2024, 76 (05) :783-795