Chick embryo chorioallantoic membrane: A biomaterial testing platform for tissue engineering applications

被引:11
作者
Vimalraj, Selvaraj [1 ]
Renugaa, Suresh [1 ]
Dhanasekaran, Anuradha [1 ]
机构
[1] Anna Univ, Ctr Biotechnol, Chennai 600025, India
关键词
Biomaterials; Chick embryo chorioallantoic membrane; (CAM); Tissue engineering; Angiogenesis; Bone; IN-VITRO; GROWTH-FACTOR; MODEL; ANGIOGENESIS; CAM; DIFFERENTIATION; NANOPARTICLES; COMPLEXES; MEDICINE; EXPOSURE;
D O I
10.1016/j.procbio.2022.11.007
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The development of biomaterials frequently relies on testing the responses of surrounding tissues to implants. A simple, affordable ex-vivo platform would be very helpful for tissue engineering. In this paper, we concentrate on the chorioallantoic membrane (CAM) of the chick embryo as a platform for evaluating the biological charac-terisation of biomaterials. The chick embryo CAM provides a quickly expanding, non-innerved vascular bed that may support tissue culture as a substitute blood supply and serve as a biomaterial testing model. Studies of CAM go beyond their more common applications in the lab; topics include tissue responses, wound healing, anti-bacterial/viral agents, angiogenic characteristics of biomaterials, CAM as bioreactors, and live bone regenera-tion. It is explored how useful CAM could be as an ex-vivo model in the field of tissue engineering.
引用
收藏
页码:81 / 91
页数:11
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