Transcranial Magnetic Stimulation in Disorders of Consciousness: An Update and Perspectives

被引：8
|
作者：
Huang, Weilong [1 ]
Chen, Qiang [1 ]
Liu, Jun [1 ]
Liu, Lin [2 ]
Tang, Jianhong [3 ]
Zou, Mingang [1 ]
Zeng, Tianxiang [1 ]
Li, Huichen [1 ]
Jiang, Qing [1 ]
Jiang, QiuHua [1 ]
机构：
[1] Ganzhou Peoples Hosp, Dept Neurosurg, Ganzhou 341000, Jiangxi, Peoples R China
[2] Gannan Med Univ, Minist Educ, Key Lab Prevent & Treatment Cardiovasc & Cerebrov, Ganzhou, Jiangxi, Peoples R China
[3] Gannan Med Univ, Lab Anim Engn Res Ctr Ganzhou, Ganzhou, Jiangxi, Peoples R China
来源：
AGING AND DISEASE | 2023年 / 14卷 / 04期
关键词：
disorders of consciousness; repetitive transcranial magnetic stimulation; treatment; patients; clinical; DORSOLATERAL PREFRONTAL CORTEX; PERSISTENT VEGETATIVE STATE; CORTICOSPINAL EXCITABILITY; UNRESPONSIVE WAKEFULNESS; CORTICAL STIMULATION; MOTOR FUNCTION; BRAIN; RTMS; RECOVERY; SAFETY;
D O I：
10.14336/AD.2022.1114
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Disorders of consciousness (DOC) is a state in which consciousness is affected by brain injuries, leading to dysfunction in vigilance, awareness, and behavior. DOC encompasses coma, vegetative state, and minimally conscious state based on neurobehavioral function. Currently, DOC is one of the most common neurological disorders with a rapidly increasing incidence worldwide. Therefore, DOC not only impacts the lives of individuals and their families but is also becoming a serious public health threat. Repetitive transcranial magnetic stimulation (rTMS) can stimulate electrical activity using a pulsed magnetic field in the brain, with great value in the treatment of chronic pain, neurological diseases, and mental illnesses. However, the clinical application of rTMS in patients with DOC is debatable. Herein, we report the recent main findings of the clinical therapeutics of rTMS for DOC, including its efficacy and possible mechanisms. In addition, we discuss the potential key parameters (timing, location, frequency, strength, and secession of rTMS applications) that affect the therapeutic efficiency of rTMS in patients with DOC. This review may help develop clinical guidelines for the therapeutic application of rTMS in DOC.
引用
收藏
页码：1171 / 1183
页数：13
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