Nucleic acid aptamer-based biosensors and their application in thrombin analysis

被引：2

作者：

Dong, Hang ^{[1
]}

Liu, Xiyu ^{[1
]}

Gan, Lu ^{[1
]}

Fan, Dianfa ^{[1
]}

Sun, Xinjun ^{[1
]}

Zhang, Zhikun ^{[1
]}

Wu, Pan ^{[1
,2
]}

机构：

[1] Guangxi Med Univ, Natl Ctr Int Res Biotargeting Theranost, Collaborat Innovat Ctr Targeting Tumor Diag & Ther, State Key Lab Targeting Oncol,Guangxi Key Lab Biot, Nanning 530021, Guangxi, Peoples R China

[2] Guangxi Med Univ, Pharmaceut Coll, Nanning 530021, Guangxi, Peoples R China

来源：

BIOANALYSIS | 2023年 / 15卷 / 09期

关键词：

aptamer; biosensor; electrochemical biosensor; optical biosensor; SURFACE-PLASMON RESONANCE; ELECTROCHEMICAL BIOSENSORS; LABEL-FREE; CHEMILUMINESCENCE; SENSOR; DNA; NANOPARTICLES; FLUORESCENCE; FERROCENE; ASSAY;

D O I：

10.4155/bio-2023-0058

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Thrombin is a multifunctional serine protease that plays an important role in coagulation and anticoagulation processes. Aptamers have been widely applied in biosensors due to their high specificity, low cost and good biocompatibility. This review summarizes recent advances in thrombin quantification using aptamer-based biosensors. The primary focus is optical sensors and electrochemical sensors, along with their applications in thrombin analysis and disease diagnosis.

引用

页码：513 / 532

页数：20

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