The current standard method for type 1 diabetes (T1D) management majorly focuses on controlling blood glucose levels with exogeneous insulin administration. Recent developments have focused on finding ways to predict and prevent the development of T1D, as well as finding a curative therapy for T1D. Such developments include ss-cell replacement therapy by islet transplantation, non-insulin adjunct therapy, gene and stem cell-based therapies, immunotherapy, and automated treatment with an artificial pancreas. In recent years, non-traditional alternative therapy has also become a popular treatment option for T1D. This review discusses the various therapeutic options for T1D currently under various stages of development, the challenges associated with the present strategies, and their potential to eventually change the way T1D is treated.
机构:
Ist Sci San Raffaele, Dept Internal Med, I-20132 Milan, Italy
Ist Sci San Raffaele, Diabet Res Inst, I-20132 Milan, Italy
Univ Vita Salute San Raffaele, I-20132 Milan, ItalyIst Sci San Raffaele, Dept Internal Med, I-20132 Milan, Italy
机构:
Univ Paris 05, Hop St Vincent de Paul, INSERM, Dept Pediat Endocrinol, F-75014 Paris, France
Univ Paris 05, Hop St Vincent de Paul, INSERM, U561, F-75014 Paris, FranceUniv Paris 05, Hop St Vincent de Paul, INSERM, Dept Pediat Endocrinol, F-75014 Paris, France
机构:
Ist Sci San Raffaele, Dept Internal Med, I-20132 Milan, Italy
Ist Sci San Raffaele, Diabet Res Inst, I-20132 Milan, Italy
Univ Vita Salute San Raffaele, I-20132 Milan, ItalyIst Sci San Raffaele, Dept Internal Med, I-20132 Milan, Italy
机构:
Univ Paris 05, Hop St Vincent de Paul, INSERM, Dept Pediat Endocrinol, F-75014 Paris, France
Univ Paris 05, Hop St Vincent de Paul, INSERM, U561, F-75014 Paris, FranceUniv Paris 05, Hop St Vincent de Paul, INSERM, Dept Pediat Endocrinol, F-75014 Paris, France