Haplotype structure of MSTN, IGF1, and BMP2 genes in Tunisian goats (Capra hircus) and their association with morphometric traits

被引：2

作者：

Chalbi, Sarra ^{[1
,2
]}

Dettori, Maria Luisa ^{[3
]}

Djemali, M'Naouer ^{[1
]}

Vacca, Giuseppe Massimo ^{[3
]}

Petretto, Elena ^{[3
]}

Pazzola, Michele ^{[3
]}

Bedhiaf-Romdhani, Sonia ^{[2
]}

机构：

[1] Natl Agron Inst Tunisia, 43 Ave Charles Nicolle, Tunis 1082, Mahrajene, Tunisia

[2] Univ Carthage, Inst Natl Rech Agron Tunisie, Lab Prod Anim & Fourrageres, Carthage, Tunisia

[3] Univ Sassari, Dipartimento Med Vet, Sassari, Italy

来源：

TROPICAL ANIMAL HEALTH AND PRODUCTION | 2023年 / 55卷 / 01期

关键词：

Morphometric traits; MSTN; IGF1; BMP2; SNP; Haplotype block; MYOSTATIN GENE MSTN; GROWTH TRAITS; MUSCLE MASS; POLYMORPHISMS; BMP-2; SHEEP;

D O I：

10.1007/s11250-022-03403-4

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

The aim of the present study was to evaluate variability and haplotype structure of twenty-eight single nucleotide polymorphisms (SNPs) at myostatin (MSTN), insulin-like growth factor 1 (IGF1), and bone morphogenetic protein 2 (BMP2) genes. Association between the polymorphic SNPs and morphometric traits was performed on a population of 263 Tunisian goats. The SNPs analyzed were all polymorphic (except one), and the three genes had different haplotype structures. Significant association of SNPs at MSTN with head length was highlighted in the Tunisian goats. The variability at IGF1 gene was associated with body length, ear length, tail length, and chest depth. For BMP2, significant association was revealed with chest depth. Significant association was also detected between linkage disequilibrium (LD) block 2 at IGF1 with body length. These findings might play a potential role in gene-assisted programs.

引用

页数：9

共 48 条

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