IFNγ, IL-4, and IL-13 upregulate IL-31 receptor alpha in airway smooth muscle cells to induce airway hyperresponsiveness in asthma

被引:0
作者
Akkenapally, Santhoshi Vani [1 ,2 ]
Yombo, Dan J. K. [3 ]
Geereddy, Bhanuprakash Reddy [2 ]
Madala, Satish K. [1 ]
机构
[1] Univ Cincinnati, Coll Med, Cincinnati, OH USA
[2] ICMR Natl Inst Nutr, Hyderabad, Telangana, India
[3] Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH 45229 USA
关键词
D O I
10.4049/jimmunol.210.Supp.67.18
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Il-13 Promotes Airway Hyperresponsiveness In Asthma Through A Pten Dependent Mechanism
    Khalifeh-Soltani, A.
    Gupta, D.
    McCarthy, D.
    Ha, A.
    Atabai, K.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 193
  • [32] Suppression of established, ongoing allergic airway inflammation (AAI) by IL-4, IL-13, and IL-4R[alpha] antagonists
    Perkins, Charles
    Orekov, Tatyana
    Khodoun, Marat
    Finkelman, Fred D.
    JOURNAL OF IMMUNOLOGY, 2006, 176 : S289 - S289
  • [33] The evolution of IL-4 and IL-13 and their receptor subunits
    Wang, Tiehui
    Secombes, Christopher J.
    CYTOKINE, 2015, 75 (01) : 8 - 13
  • [34] The TH2 cytokines, IL-4 and IL-13, induce human bronchial smooth muscle proliferation
    Bossé, Y
    Stankova, J
    Rola-Pleszczynski, M
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2006, 117 (03) : 721 - 721
  • [35] Polymorphisms in the IL-13 and IL-4 receptor alpha genes and allergic rhinitis
    Jeong Joong Kim
    Jung Youl Min
    Jae Hoon Lee
    European Archives of Oto-Rhino-Laryngology, 2007, 264 : 395 - 399
  • [36] Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis.
    Neis, Mark M.
    Peters, Bettina
    Dreuw, Alexandra
    Wenzel, Joerg
    Bieber, Thomas
    Mauch, Cornelia
    Krieg, Thomas
    Stanzel, Sven
    Heinrich, Peter C.
    Merk, Hans F.
    Bosio, Andreas
    Baron, Jens M.
    Hermanns, Heike M.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2006, 118 (04) : 930 - 937
  • [37] Polymorphisms in the IL-13 and IL-4 receptor alpha genes and allergic rhinitis
    Kim, Jeong Joong
    Min, Jung Youl
    Lee, Jae Hoon
    EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2007, 264 (04) : 395 - 399
  • [38] Requirement for IL-13 independently of IL-4 in experimental asthma
    Grunig, G
    Warnock, M
    Wakil, AE
    Venkayya, R
    Brombacher, F
    Rennick, DM
    Sheppard, D
    Mohrs, M
    Donaldson, DD
    Locksley, RM
    Corry, DB
    FASEB JOURNAL, 1999, 13 (04) : A318 - A318
  • [39] IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways
    Manson, Martijn L.
    Safholm, Jesper
    James, Anna
    Johnsson, Anna-Karin
    Bergman, Per
    Al-Ameri, Mamdoh
    Orre, Ann-Charlotte
    Karrman-Mardh, Carina
    Dahlen, Sven-Erik
    Adner, Mikael
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2020, 145 (03) : 808 - +
  • [40] Requirement for IL-13 independently of IL-4 in experimental asthma
    Grünig, G
    Warnock, M
    Wakil, AE
    Venkayya, R
    Brombacher, F
    Rennick, DM
    Sheppard, D
    Mohrs, M
    Donaldson, DD
    Locksley, RM
    Corry, DB
    SCIENCE, 1998, 282 (5397) : 2261 - 2263