Transition Metal-Catalyzed Migratory Tsuji-Trost Reaction

被引：4

作者：

Chen, Xian-Xiao ^{[1
]}

He, Zhi-Tao ^{[1
,2
]}

机构：

[1] Univ Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, R China, Shanghai 200032, Peoples R China

[2] Univ Chinese Acad Sci, Hangzhou Inst Adv Study, Sch Chem & Mat Sci, Hangzhou 310024, Peoples R China

来源：

CHEMCATCHEM | 2023年 / 15卷 / 22期

基金：

中国国家自然科学基金;

关键词：

Migratory Tsuji-Trost reaction; Leaving group migration; Olefin migration; Palladium catalyst; ALLYLIC SUBSTITUTION; HYDROALKYLATION; 1,3-DIENES; ALKYLATION; MECHANISM; CENTERS; DIENES; AMINES; AZIDES;

D O I：

10.1002/cctc.202301073

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Beyond the scope of classical Tsuji-Trost reaction, an alkene bearing a remote leaving group is not considered as a potential substrate for allylation. The concept of migratory Tsuji-Trost reaction focuses on the transformations with this type of substrates. Two pathways including olefin migration and leaving group migration to form typical allyl intermediate for following substitution have been explored to demonstrate the feasibility of this new concept. The development of migratory Tsuji-Trost reaction as a new reaction area via olefin migration or leaving group migration to generate critical pi-allyl Pd intermediate was summarized.image

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页数：6

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