Value of procollagen type I N-terminal propeptide (P1NP) as a bone formation marker

被引：0

作者：

Oremek, G. M. ^{[1
]}

Holzgreve, F. ^{[2
]}

Maurer-Grubinger, C. ^{[3
]}

Diaremes, P. ^{[3
]}

Erbe, C. ^{[4
]}

Ohlendorf, D. ^{[2
,5
]}

机构：

[1] Goethe Univ Frankfurt, Inst Arbeitsmed Sozialmed & Umweltmed, Abt Labordiagnost, Frankfurt Am Main, Germany

[2] Goethe Univ Frankfurt, Inst Arbeitsmed Sozialmed & Umweltmed, Frankfurt Am Main, Germany

[3] Goethe Univ Frankfurt, Klin Orthopad, Frankfurt Am Main, Germany

[4] Johannes Gutenberg Univ Mainz, Univ Med Johannes Gutenberg Univ Mainz, Klin Zahn Mund & Kieferkrankheiten, Poliklin Kieferorthopad, Mainz, Germany

[5] Goethe Univ Frankfurt, Inst Arbeitsmed Sozialmed & Umweltmed, Frankfurt Am Main, Germany

来源：

ZENTRALBLATT FUR ARBEITSMEDIZIN ARBEITSSCHUTZ UND ERGONOMIE | 2024年 / 74卷 / 01期

关键词：

Biomarkers; Procollagen type I N-terminal; propeptide; Immunological methods; Bone; metastases; Diagnostics; ACID-PHOSPHATASE ISOFORMS; BIOCHEMICAL MARKERS; SERUM MARKER; METASTASIS; 5B; METABOLISM; MECHANISMS; BIOMARKERS; COLLAGEN; DISEASE;

D O I：

10.1007/s40664-023-00518-9

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

This informative summary of the bone formation marker procollagen type I N-terminal propeptide (P1NP) is published as part of the series "Biomarkers" of the Zentralblatt fur Arbeitsmedizin, Arbeitsschutz und Ergonomie and is intended as a training tool for occupational physicians. It deals with the increasingly more frequent use of the determination of specificmarkers in so-called managerial screening and check-up examinations. The marker P1NP shows a high sensitivity and specificity but is generally not suitable as a screening parameter for early diagnosis or for prevention as it is a marker for monitoring treatment, progression and recurrence of bone metastases.

引用

页码：43 / 48

页数：6

共 67 条

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