Relationship between preoperative lymphocyte to monocyte ratio and surgery outcome in type A aortic dissection

被引:3
作者
Ma, Ming [1 ,2 ,3 ]
Zhu, Feng [1 ,2 ,3 ]
Fan, Fudong [1 ,2 ,3 ]
Pan, Jun [1 ,2 ,3 ]
Cao, Hailong [1 ,2 ,3 ]
Zhou, Qing [1 ,2 ,3 ]
Wang, Dongjin [1 ,2 ,3 ]
机构
[1] Nanjing Med Univ, Nanjing Drum Tower Hosp, Clin Coll, Nanjing, Peoples R China
[2] Nanjing Univ, Dept Thorac & Cardiovasc Surg, Affiliated Drum Tower Hosp, Med Sch, Nanjing, Peoples R China
[3] Nanjing Univ, Inst Cardiothorac Vasc Dis, Nanjing, Peoples R China
基金
中国国家自然科学基金;
关键词
aortic dissection; surgery outcome; lymphocyte; monocyte; preoperative; ACUTE KIDNEY INJURY; RISK-FACTORS; INFLAMMATION; NEUTROPHIL;
D O I
10.3389/fsurg.2022.1103290
中图分类号
R61 [外科手术学];
学科分类号
摘要
BackgroundLymphocyte-to-monocyte ratio (LMR) is associated with the mortality of cardiovascular diseases. However, the relationship between preoperative LMR and the prognosis of patients with Stanford type A aortic dissection (TAAD) undergoing surgical treatment remains to be determined. MethodsWe enrolled 879 patients with TAAD undergoing surgical treatment between January 2018 and December 2021. Patients were divided into two groups: the Deceased group and the Survived group. The baseline clinical and operative characteristics of the two groups were compared and analyzed. ResultsIn univariate and multivariate logistic regression analysis, the association between LMR and in-hospital mortality was significant, and LMR (OR = 1.598, 95% CI 1.114-2.485, P = 0.022) remained significant after adjusting for confounders. ConclusionLower LMR may be independently associated with higher in-hospital mortality in TAAD undergoing surgical treatment.
引用
收藏
页数:8
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