A Brief Review on Schiff Base, Synthesis, and Their Antimicrobial Activities

被引:8
作者
Dhedan, Ruaa M. [1 ]
Alsahib, Sanaa A. [1 ]
Ali, Rana Abid [2 ]
机构
[1] Univ Baghdad, Coll Sci Women, Dept Chem, Baghdad, Iraq
[2] Univ Baghdad, Coll Sci, Dept Chem, Baghdad 10001, Iraq
关键词
Schiff base; method of synthesis; biological activity; ONE-POT SYNTHESIS; IN-VITRO; METAL-COMPLEXES; MANNICH-BASES; ANTIVIRAL ACTIVITY; PHARMACOLOGICAL EVALUATION; CYTOTOXICITY EVALUATION; ANTIOXIDANT ACTIVITIES; BIOLOGICAL-ACTIVITY; ANTICANCER ACTIVITY;
D O I
10.1134/S1068162023080046
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Schiff base chemsitry includes compounds that attracted the attention of research scope from the early years. Consequently, the Schiff base constitutes a significant source of compounds for new pharmacological developments. Several Schiff bases, including derivatives, were synthesized and assessed for biological activities they possess, containing antimicrobial, antioxidant, anti-inflammatory, anti-tuberculosis, anticonvulsants, anxiolytics, antidepressant, anticancer, antihypertensive,and anti-fungal activity. The Schiff Base research, including composites with a lower-side effect, and extra specific activity and remains a dynamic zone of debate in medicinal chemistry. The current wrok elaborately discusses the medicinal chemistry and its bio-logical qualities.
引用
收藏
页码:S31 / S52
页数:22
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