Outcomes of Elective and Non-elective Fenestrated-branched Endovascular Aortic Repair for Treatment of Thoracoabdominal Aortic Aneurysms

被引:23
作者
Dias-Neto, Marina [1 ]
Vacirca, Andrea [1 ]
Huang, Ying [1 ]
Baghbani-Oskouei, Aidin [1 ]
Jakimowicz, Tomasz [2 ]
Mendes, Bernardo C. [3 ]
Kolbel, Tilo [4 ]
Sobocinski, Jonathan [5 ,6 ]
Bertoglio, Luca [7 ,8 ]
Mees, Barend [9 ]
Gargiulo, Mauro [10 ,11 ]
Dias, Nuno [12 ,13 ]
Schanzer, Andres [14 ]
Gasper, Warren [15 ]
Beck, Adam W. [16 ]
Farber, Mark A. [17 ]
Mani, Kevin [18 ]
Timaran, Carlos [19 ]
Schneider, Darren B. [20 ]
Pedro, Luis Mendes [21 ,22 ,23 ]
Tsilimparis, Nikolaos [24 ]
Haulon, Stephan [25 ]
Sweet, Matthew P. [26 ]
Ferreira, Emilia [27 ]
Eagleton, Matthew [28 ]
Yeung, Kak Khee [29 ]
Khashram, Manar [30 ,31 ]
Jama, Katarzyna [2 ]
Panuccio, Giuseppe [4 ]
Rohlffs, Fiona [4 ]
Mesnard, Thomas [5 ,6 ]
Chiesa, Roberto [7 ,8 ]
Kahlberg, Andrea [7 ,8 ]
Schurink, Geert Willem [9 ]
Lemmens, Charlotte [9 ]
Gallitto, Enrico [10 ,11 ]
Faggioli, Gianluca [10 ,11 ]
Karelis, Angelos [12 ,13 ]
Parodi, Ezequiel [17 ]
Gomes, Vivian [17 ]
Wanhainen, Anders [18 ]
Habib, Mohammed [18 ]
Colon, Jesus Porras [19 ]
Pavarino, Felipe [19 ]
Baig, Mirza S. [19 ]
Melo, Ryan Eduardo Costeloe De [21 ,22 ,23 ,24 ]
Crawford, Sean [25 ]
Zettervall, Sara L. [26 ]
Garcia, Rita [27 ]
Ribeiro, Tiago [27 ]
机构
[1] Univ Texas Hlth Sci Ctr Houston, McGovern Med Sch, Adv Aort Res Program, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USA
[2] Med Univ Warsaw, Warsaw, Poland
[3] Mayo Clin, Div Vasc & Endovasc Surg, Rochester, MN USA
[4] Univ Med Ctr Eppendorf UKE, Hamburg, Germany
[5] Univ Lille, CHU Lille, Aort Ctr, Vasc Surg, Lille, France
[6] Univ Lille, CHU Lille, INSERM U1008, Lille, France
[7] Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Dept Vasc Surg, Milan, Italy
[8] Univ & ASST Spedali Civili Hosp Brescia, Dept Sperimental & Clin Sci DSCS, Brescia, Italy
[9] Maastricht Univ, Med Ctr, Dept Vasc Surg, Maastricht, Netherlands
[10] Univ Bologna, Vasc Surg, DIMEC, Bologna, Italy
[11] IRCCS Univ Hosp Policlin S Orsola, Vasc Surg Unit, Bologna, Italy
[12] Skane Univ Hosp, Vasc Ctr, Dept Thorac Surg & Vasc Dis, Malmo, Sweden
[13] Lund Univ, Dept Clin Sci, Malmo, Sweden
[14] Univ Massachusetts, Med Sch, Worcester, MA USA
[15] Univ Calif San Francisco, San Francisco, CA USA
[16] Univ Alabama Birmingham, Birmingham, AL USA
[17] Univ N Carolina, Dept Surg, Div Vasc Surg, Chapel Hill, NC USA
[18] Uppsala Univ, Dept Surg Sci, Div Vasc Surg, Uppsala, Sweden
[19] Univ Texas Southwestern, Clin Heart & Vasc Ctr, Dallas, TX USA
[20] Univ Penn, Perelman Sch Med, Div Vasc Surg & Endovasc Therapy, Philadelphia, PA USA
[21] Ctr Hosp Univ Lisboa Norte, Dept Vasc Surg, Lisbon, Portugal
[22] Univ Lisbon, Fac Med, Lisbon, Portugal
[23] Univ Lisboa CCULRISE, Ctr Cardiovasc, Lisbon, Portugal
[24] Ludwig Maximilians Univ Hosp, Dept Vasc Surg, Munich, Germany
[25] Univ Paris Saclay, Hop Marie Lannelongue, Aort Ctr, Grp Hosp Paris St Joseph, Paris, France
[26] Univ Washington, Dept Surg, Div Vasc Surg, Seattle, WA USA
[27] Ctr Hosp Univ Lisboa Cent, Hosp Santa Marta, Dept Angiol & Vasc Surg, Lisbon, Portugal
[28] Harvard Med Sch, Massachusetts Gen Hosp, Div Vasc & Endovasc Surg, Boston, MA USA
[29] Amsterdam UMC, VU Med Ctr, Amsterdam Cardiovasc Sci, Dept Vasc Surg, Amsterdam, Netherlands
[30] Waikato Hosp, Dept Vasc Surg, Hamilton, New Zealand
[31] Univ Auckland, Dept Surg, Auckland, New Zealand
关键词
fenestrated-branched endovascular aortic repair; thoracoabdominal aortic aneurysm; non-elective repair; elective repair; MIDTERM OUTCOMES; ENDOGRAFTS; MORTALITY;
D O I
10.1097/SLA.0000000000005986
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objective: To describe outcomes after elective and non-elective fenestrated-branched endovascular aortic repair (FB-EVAR) for thoracoabdominal aortic aneurysms (TAAAs). Background: FB-EVAR has been increasingly utilized to treat TAAAs; however, outcomes after non-elective versus elective repair are not well described. Methods: Clinical data of consecutive patients undergoing FB-EVAR for TAAAs at 24 centers (2006-2021) were reviewed. Endpoints including early mortality and major adverse events (MAEs), all-cause mortality, and aortic-related mortality (ARM), were analyzed and compared in patients who had non-elective versus elective repair. Results: A total of 2603 patients (69% males; mean age 72 +/- 10 year old) underwent FB-EVAR for TAAAs. Elective repair was performed in 2187 patients (84%) and non-elective repair in 416 patients [16%; 268 (64%) symptomatic, 148 (36%) ruptured]. Non-elective FB-EVAR was associated with higher early mortality (17% vs 5%, P < 0.001) and rates of MAEs (34% vs 20%, P < 0.001). Median follow-up was 15 months ( interquartile range, 7-37 months). Survival and cumulative incidence of ARM at 3 years were both lower for non-elective versus elective patients (50 +/- 4% vs 70 +/- 1% and 21 +/- 3% vs 7 +/- 1%, P < 0.001). On multivariable analysis, non-elective repair was associated with increased risk of all-cause mortality ( hazard ratio, 1.92; 95% CI] 1.50-2.44; P < 0.001) and ARM (hazard ratio, 2.43; 95% CI, 1.63-3.62; P < 0.001). Conclusions: Non-elective FB-EVAR of symptomatic or ruptured TAAAs is feasible, but carries higher incidence of early MAEs and increased all-cause mortality and ARM than elective repair. Long-term follow-up is warranted to justify the treatment.
引用
收藏
页码:568 / 577
页数:10
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