Application of N-doped carbon quantum dots as a resonance light scattering probe for determination of fluvoxamine

被引:3
作者
Fazl, Fariba [1 ]
Gholivand, Mohammad Bagher [1 ]
机构
[1] Razi Univ, Fac Chem, Dept Analyt Chem, Kermanshah, Iran
关键词
Resonance light scattering; N-doped carbon quantum dots; Drug monitoring; Fluvoxamine; FLUORESCENCE;
D O I
10.1016/j.jphotochem.2023.115368
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Resonance light scattering (RLS) as a simple, rapid, inexpensive method was introduced for the determination of fluvoxamine in real samples (blood serum and commercial tablet) based on nitrogen-doped carbon quantum dots (N-CQDs) probe. The N-CQDs were characterized using various techniques such as UV-Vis spectroscopy, fluo-rescence spectroscopy, Transmission Electron Microscopy (TEM), X-Ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), and Dynamic Light Scattering (DLS), which revealed their size distribution range to be between 1 and 6 nm. The optimized conditions resulted in a linear response between 0.01 and 12.0 mg L-1 and a limit of detection of 5 mu g/L, making this method suitable for analyzing fluvoxamine in blood serum and commercial tablet samples.
引用
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页数:7
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