Osilodrostat in Cushing's disease: The risk of delayed adrenal insufficiency should be carefully monitored

被引：13
|
作者：
Castinetti, Frederic [1 ]
Amodru, Vincent [1 ]
Brue, Thierry [1 ]
机构：
[1] Aix Marseille Univ, La Conception Hosp, AP HM, INSERM,MMG,Marmara Inst,Dept Endocrinol, Marseille, France
来源：
CLINICAL ENDOCRINOLOGY | 2023年 / 98卷 / 04期
关键词：
Adrenal; adrenal insufficiency; cortisol; Cushing's disease; Pituitary; steroidogenesis inhibitor; 11-BETA-HYDROXYLASE INHIBITOR; MULTICENTER; EFFICACY; SAFETY;
D O I：
10.1111/cen.14551
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Antisecretory data shows a highly effective and prolonged blockade of cortisol secretion with osilodrostat. The drawback is the occurrence of adrenal insufficiency (AI) in roughly a quarter of treated patients. In this short manuscript, we report three cases of atypical adrenal insufficiency with osilodrostat.
引用
收藏
页码：629 / 630
页数：2
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