The treatment of obesity in children and adolescents: consensus position statement of the Italian society of pediatric endocrinology and diabetology, Italian Society of Pediatrics and Italian Society of Pediatric Surgery

被引：24

作者：

Maffeis, Claudio ^{[1
]}

Olivieri, Francesca ^{[1
]}

Valerio, Giuliana ^{[2
]}

Verduci, Elvira ^{[3
]}

Licenziati, Maria Rosaria ^{[4
]}

Calcaterra, Valeria ^{[5
,6
]}

Pelizzo, Gloria ^{[7
]}

Salerno, Mariacarolina ^{[8
]}

Staiano, Annamaria ^{[8
]}

Bernasconi, Sergio ^{[9
]}

Buganza, Raffaele ^{[10
]}

Crino, Antonino ^{[11
]}

Corciulo, Nicola ^{[12
]}

Corica, Domenico ^{[13
]}

Destro, Francesca ^{[7
]}

Di Bonito, Procolo ^{[14
]}

Di Pietro, Mario ^{[15
]}

Di Sessa, Anna ^{[16
]}

deSanctis, Luisa ^{[17
]}

Faienza, Maria Felicia ^{[18
]}

Filannino, Grazia ^{[19
]}

Fintini, Danilo ^{[20
]}

Fornari, Elena ^{[1
]}

Franceschi, Roberto ^{[21
]}

Franco, Francesca ^{[22
]}

Franzese, Adriana ^{[8
]}

Giusti, Lia Franca ^{[23
]}

Grugni, Graziano ^{[24
]}

Iafusco, Dario ^{[16
]}

Iughetti, Lorenzo ^{[25
]}

Lera, Riccardo ^{[26
]}

Limauro, Raffaele ^{[27
]}

Maguolo, Alice ^{[1
]}

Mancioppi, Valentina ^{[1
]}

Manco, Melania ^{[28
]}

Del Giudice, Emanuele Miraglia ^{[16
]}

Morandi, Anita ^{[1
]}

Moro, Beatrice ^{[29
]}

Mozzillo, Enza ^{[8
]}

Rabbone, Ivana ^{[30
]}

Peverelli, Paola ^{[31
]}

Predieri, Barbara ^{[25
]}

Purromuto, Salvo ^{[32
]}

Stagi, Stefano ^{[33
]}

Street, Maria Elisabeth ^{[34
]}

Tanas, Rita ^{[35
]}

Tornese, Gianluca ^{[36
]}

Umano, Giuseppina Rosaria ^{[16
]}

Wasniewska, Malgorzata ^{[13
]}

机构：

[1] Univ Verona, Sect Pediat Diabet & Metab, Dept Surg Dent Pediat & Gynecol, Verona, Italy

[2] Parthenope Univ Naples, Dept Movement Sci & Wellbeing, Naples, Italy

[3] Univ Milan, Vittore Buzzi Childrens Hosp, Dept Hlth Sci, Dept Pediat, Milan, Italy

[4] Santobono Pausilipon Childrens Hosp, Dept Neurosci, Neuro Endocrine Dis & Obes Unit, Naples, Italy

[5] Vittore Buzzi Childrens Hosp, Dept Pediat, Milan, Italy

[6] Univ Pavia, Dept Internal Med & Therapeut, Pavia, Italy

[7] Vittore Buzzi Childrens Hosp, Dept Pediat Surg, Milan, Italy

[8] Univ Naples Federico II, Sect Pediat, Dept Traslat Med Sci, Naples, Italy

[9] Univ Parma, Microbiome Reaserch Hub, Parma, Italy

[10] Univ Turin, Pediat Endocrinol Unit, Dept Publ Hlth & Pediat Sci, Turin, Italy

[11] IRCCS, Bambino Gesu Children Hosp, Autoimmune Endocrine Dis Unit, Rome, Italy

[12] Hosp Gallipoli, Pediat Unit, Lecce, Italy

[13] Univ Messina, Dept Human Pathol Adulthood & Childhood, Messina, Italy

[14] S Maria Delle Grazie Hosp, Dept Internal Med, Naples, Italy

[15] Hosp Teramo & Atri, Pediat & Neonatal Unit, Teramo, Italy

[16] Univ Campania L Vanvitelli, Dept Woman Child & Gen & Specialized Surg, Naples, Italy

[17] Univ Turin, Dept Sci Publ Hlth & Pediat, Turin, Italy

[18] Univ Bari, Dept Precis & Regenerat Med & Ionan Area, Bari, Italy

[19] Ostuni Hosp, Pediat Unit, Brindisi, Italy

[20] IRCCS, Bambino Gesu Children Hosp, Refernce Ctr Prader Willi Syndrome Endocrinol & D, Rome, Italy

[21] APSS Trento, Pediat Unit, S Chiara Hosp, Trento, Italy

[22] Hosp Udine, Dept Pediat, Azienda Sanit Univ Friuli Cent, Udine, Italy

[23] Italian Soc Pediat Endocrinol & Diabetol SIEDP, Lucca, Italy

[24] IRCCS, Ist Auxol Italiano, Div Auxol, Verbania, Italy

[25] Univ Modena & Reggio Emilia, Dept Med & Surg Sci Mother Children & Adults, Pediat Unit, Modena, Italy

[26] Italian Soc Pediat Endocrinol & Diabetol SIEDP, Alessandria, Italy

[27] Local Hlth Unit Napoli, 3 Sud, Naples, Italy

[28] Childrens Hosp Bambino Gesu, Res Area Multifactorial Dis, Rome, Italy

[29] AULSS 6 Euganea, Complesso Ai Colli, UOSD Diabetol, Padua, Italy

[30] Univ Piemonte Orientale, Div Pediat, Dept Hlth Sci, Novara, Italy

[31] Hosp Belluno, Dept Pediat & Gynecol, Belluno, Italy

[32] ASP Ragusa, Pediat Obes Unit, Ragusa, Italy

[33] Univ Florence, IRCCS, Meyer Childrens Hosp, Dept Hlth Sci, Florence, Italy

[34] Univ Parma, Univ Hosp Parma, Dept Med & Surg, Unit Paediat, Parma, Italy

[35] Italian Soc Pediat Endocrinol & Diabetol SIEDP, Ferrara, Italy

[36] IRCCS Burlo Garofolo, Inst Maternal & Child Hlth, Trieste, Italy

来源：

ITALIAN JOURNAL OF PEDIATRICS | 2023年 / 49卷 / 01期

关键词：

Children; Adolescents; Obesity; Treatment; Nutrition; Physical activity; Cognitive and family-based behavior therapy; Drug; Bariatric surgery; RANDOMIZED CONTROLLED-TRIAL; LAPAROSCOPIC SLEEVE GASTRECTOMY; GLP-1 ANALOG LIRAGLUTIDE; LIFE-STYLE INTERVENTION; BARIATRIC SURGERY; CHILDHOOD OBESITY; WEIGHT-LOSS; PHYSICAL-ACTIVITY; INSULIN-RESISTANCE; STOP HYPERTENSION;

D O I：

10.1186/s13052-023-01458-z

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

This Position Statement updates the different components of the therapy of obesity (lifestyle intervention, drugs, and surgery) in children and adolescents, previously reported in the consensus position statement on pediatric obesity of the Italian Society of Pediatric Endocrinology and Diabetology and the Italian Society of Pediatrics. Lifestyle intervention is the first step of treatment. In children older than 12 years, pharmacotherapy is the second step, and bariatric surgery is the third one, in selected cases. Novelties are available in the field of the medical treatment of obesity. In particular, new drugs demonstrated their efficacy and safety and have been approved in adolescents. Moreover, several randomized control trials with other drugs are in process and it is likely that some of them will become available in the future. The increase of the portfolio of treatment options for obesity in children and adolescents is promising for a more effective treatment of this disorder.

引用

页数：18

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