Pressure-Volume Profiles in Heart Failure Across Sexes and Phenotypes

被引:3
作者
Kittipibul, Veraprapas [1 ]
Yaranov, Dmitry M. [2 ]
Jefferies, John L. [3 ]
Silver, Marc A. [4 ]
Burkhoff, Daniel [5 ]
Rao, Vishal N. [1 ,6 ]
Biegus, Jan [7 ]
Ponikowski, Piotr [7 ]
Fudim, Marat [1 ,6 ]
机构
[1] Duke Univ, Dept Med, Div Cardiol, Med Ctr, Durham, NC 27710 USA
[2] Baptist Mem Hosp, Dept Cardiol, Memphis, TN USA
[3] Univ Tennessee Hlth Sci Ctr, Cardiovasc Inst, Memphis, TN USA
[4] Rosalind Franklin Univ, Chicago Med Sch, N Chicago, IL USA
[5] Cardiovasc Res Fdn, New York, NY USA
[6] Duke Clin Res Inst, Durham, NC 27701 USA
[7] Med Univ, Inst Heart Dis, Wroclaw, Poland
关键词
Heart failure; CardioMEMS; Blood volume analysis; BLOOD-VOLUME;
D O I
10.1007/s12265-022-10345-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Studies have shown poor correlation between intra-cardiac pressures and blood volume (BV) measurements including HF. The impact of sex and left ventricular ejection fraction (LVEF) on this relationship has not been studied. We obtained pressure (pulmonary artery diastolic pressure (PADP)) and volume (total blood volume (TBV) and estimated stress blood volume (eSBV)) measurements from HF patients at the time of CardioMEMS implantation. A total of 20 patients were included. There was no significant difference between PADP, TBV, and eSBV between sexes. There was only a moderate correlation between PADP and eSBV in men but not in women or with TBV in both sexes. HFrEF had higher PADP and eSBV than HFpEF. There was a consistent lack of correlation between PADP and both TBV and eSBV. Further studies evaluating mid- to long-term implications of pressure-volume profiles as well as changes following decongestion therapy are warranted to better understand the pressure-volume interplay and determine appropriate decongestion strategy for each pressure-volume phenotype.
引用
收藏
页码:751 / 753
页数:3
相关论文
共 7 条
[1]   PREDICTION OF NORMAL BLOOD-VOLUME - RELATION OF BLOOD-VOLUME TO BODY HABITUS [J].
FELDSCHUH, J ;
ENSON, Y .
CIRCULATION, 1977, 56 (04) :605-612
[2]   Venous Tone and Stressed Blood Volume in Heart Failure JACC Review Topic of the Week [J].
Fudim, Marat ;
Kaye, David M. ;
Borlaug, Barry A. ;
Shah, Sanjiv J. ;
Rich, Stuart ;
Kapur, Navin K. ;
Costanzo, Maria Rosa ;
Brener, Michael, I ;
Sunagawa, Kenji ;
Burkhoff, Daniel .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2022, 79 (18) :1858-1869
[3]   Effect of aggressive diuresis in acute heart failure with reduced and preserved ejection fraction [J].
He, Xin ;
Dong, Bin ;
Xue, Ruicong ;
Zhao, Jingjing ;
Wu, Zexuan ;
Wu, Yuzhong ;
Zhou, Yuanyuan ;
Wu, Dexi ;
Dong, Yugang ;
He, Jiangui ;
Liu, Chen .
ESC HEART FAILURE, 2021, 8 (04) :3248-3256
[4]   Blood Volume Determination, A Nuclear Medicine Test in Evolution [J].
Margouleff, Donald .
CLINICAL NUCLEAR MEDICINE, 2013, 38 (07) :534-537
[5]   Understanding the Heterogeneity in Volume Overload and Fluid Distribution in Decompensated Heart Failure Is Key to Optimal Volume Management Role for Blood Volume Quantitation [J].
Miller, Wayne L. ;
Mullan, Brian P. .
JACC-HEART FAILURE, 2014, 2 (03) :298-305
[6]   Effects of Vasodilation in Heart Failure With Preserved or Reduced Ejection Fraction Implications of Distinct Pathophysiologies on Response to Therapy [J].
Schwartzenberg, Shmuel ;
Redfield, Margaret M. ;
From, Aaron M. ;
Sorajja, Paul ;
Nishimura, Rick A. ;
Borlaug, Barry A. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2012, 59 (05) :442-451
[7]   Discordance of Pressure and Volume: Potential Implications for Pressure-Guided Remote Monitoring in Heart Failure [J].
Yaranov, Dmitry M. ;
Jefferies, John L. ;
Silver, Marc A. ;
Burkhoff, Daniel ;
Rao, Vishal N. ;
Fudim, Marat .
JOURNAL OF CARDIAC FAILURE, 2022, 28 (05) :870-872