Age-at-injury effects of microglial activation following traumatic brain injury: implications for treatment strategies

被引：0

作者：

Ramesh Raghupathi ^{[1
,2
]}

Jimmy W.Huh ^{[3
]}

机构：

[1] Program in Neuroscience, Drexel University College of Medicine

[2] Department of Neurobiology and Anatomy, Drexel University College of Medicine

[3] Department of Anesthesiology and Critical Care, Children’s Hospital of Philadelphia

来源：

Neural Regeneration Research | 2017年 / 12卷 / 05期

关键词：

TBI; Age-at-injury effects of microglial activation following traumatic brain injury; implications for treatment strategies;

D O I：

暂无

中图分类号：

R726.5 [小儿各生理系统外科学];

学科分类号：

100202 ;

摘要：

Traumatic brain injury(TBI)remains one of the leading causes of disability and death in infants and children.Studies have demonstrated that the youngest age group(especially≤4 years old)exhibit worse functional outcome following moderate to severe TBI compared to older children or adults(Anderson et al.,2005;Emami et al.,2017).These data suggest that age-at-injury may be an important determinant of outcome,as damage to the developing brain at a young age likely disrupts normal

引用

页码：741 / 742

页数：2

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