The role of microtubule-associated protein 1B in axonal growth and neuronal migration in the central nervous system

被引：0
|
作者：
Maoguang Yang
机构：
来源：
NeuralRegenerationResearch | 2012年 / 7卷 / 11期
基金：
中国国家自然科学基金;
关键词：
microtubule-associated protein 1B; central nervous system; axonal regeneration; axonal development; axon guidance; neuronal migration;
D O I：
暂无
中图分类号：
R329 [人体组织学];
学科分类号：
100101 ;
摘要：
In this review,we discuss the role of microtubule-associated protein 1B(MAP1B) and its phosphorylation in axonal development and regeneration in the central nervous system.MAP1B exhibits similar functions during axonal development and regeneration.MAP1B and phosphorylated MAP1B in neurons and axons maintain a dynamic balance between cytoskeletal components,and regulate the stability and interaction of microtubules and actin to promote axonal growth,neural connectivity and regeneration in the central nervous system.
引用
收藏
页码：842 / 848
页数：7
相关论文
共 50 条
  • [11] Microtubule-associated protein 1B controls directionality of growth cone migration and axonal branching in regeneration of adult dorsal root ganglia neurons
    Bouquet, C
    Soares, S
    von Boxberg, Y
    Ravaille-Veron, M
    Propst, F
    Nothias, F
    JOURNAL OF NEUROSCIENCE, 2004, 24 (32): : 7204 - 7213
  • [12] Microtubule-associated protein 1B is involved in the initial stages of axonogenesis in peripheral nervous system cultured neurons
    Gonzalez-Billault, C
    Owen, R
    Gordon-Weeks, PR
    Avila, J
    BRAIN RESEARCH, 2002, 943 (01) : 56 - 67
  • [13] Microtubule-associated protein 1B function during normal development, regeneration, and pathological conditions in the nervous system
    Gonzalez-Billault, C
    Jimenez-Mateos, EM
    Caceres, A
    Diaz-Nido, J
    Wandosell, F
    Avila, J
    JOURNAL OF NEUROBIOLOGY, 2004, 58 (01): : 48 - 59
  • [14] Phosphorylation sites of microtubule-associated protein 1B (MAP 1B) are involved in axon growth and regeneration
    Yuya Ishikawa
    Masayasu Okada
    Atsuko Honda
    Yasuyuki Ito
    Atsushi Tamada
    Naoto Endo
    Michihiro Igarashi
    Molecular Brain, 12
  • [15] Microtubule-associated protein 1B dysregulates microtubule dynamics and neuronal mitochondrial transport in spinal muscular atrophy
    Bora, Gamze
    Hensel, Niko
    Rademacher, Sebastian
    Koyunoglu, Dila
    Sunguroglu, Merve
    Aksu-Menges, Evrim
    Balci-Hayta, Burcu
    Claus, Peter
    Erdem-Yurter, Hayat
    HUMAN MOLECULAR GENETICS, 2020, 29 (24) : 3935 - 3944
  • [16] Phosphorylation sites of microtubule-associated protein 1B (MAP 1B) are involved in axon growth and regeneration
    Ishikawa, Yuya
    Okada, Masayasu
    Honda, Atsuko
    Ito, Yasuyuki
    Tamada, Atsushi
    Endo, Naoto
    Igarashi, Michihiro
    MOLECULAR BRAIN, 2019, 12 (01)
  • [17] Microtubule-associated protein 1B: Novel paraneoplastic biomarker
    Gadoth, Avi
    Kryzer, Thomas J.
    Fryer, Jim
    McKeon, Andrew
    Lennon, Vanda A.
    Pittock, Sean J.
    ANNALS OF NEUROLOGY, 2017, 81 (02) : 266 - 277
  • [18] Microtubule-associated protein 1B in axon elongation and neurotransmission
    Gonzalez-Billault, C.
    JOURNAL OF NEUROCHEMISTRY, 2013, 125 : 57 - 57
  • [19] PHOSPHORYLATION OF MICROTUBULE-ASSOCIATED PROTEIN IB AND AXONAL GROWTH
    GORDONWEEKS, PR
    JOHNSTONE, M
    BUSH, M
    BIOCHEMICAL SOCIETY TRANSACTIONS, 1995, 23 (01) : 37 - 40
  • [20] Delayed development of nervous system in mice homozygous for disrupted microtubule-associated protein 1B (MAP1B) gene
    Takei, Y
    Kondo, S
    Harada, A
    Inomata, S
    Noda, T
    Hirokawa, N
    JOURNAL OF CELL BIOLOGY, 1997, 137 (07): : 1615 - 1626
12345