<正> We have previously reported that the diameter of the inferior vena cava(IVC) reflects the amount of body fluid in hemodi-alyzed (HD) patients. Trie present study was undertaken to depict the criteria of IVC diameters for determining dry weight (DW) in a-nuric HD patients. In healthy subjects, the maximal diameters during quiet expiration (IVCe) and the minimal diameters during quiet inspiration (IVCi) were (16.7±3.2) and (5.7±5.4)mm, respectively (mean±SD) .The collapsibility index (CI, 1- FVCi/IVCe) , which inversely correlates with the central venous pressure,was 0.68±0.29. In anuric HD patients, the IVCe/CI values before and after HD were 14.9±3.2/0.68±0.24 and 8.2±2.3/0.94±0.09, respectively. IVCe decreased proportionally to the amount of ultrafil-tration. In HD patients with hypervolemic pulmonary edema, the IVCe and CI values were 22.4+2.9 and 0.22+0.11, respectively. We proposed that IVCe/CI after HD is (8±3)mm/0.9±0.1 as the markers of DW in anuric HD patients and that an IVCe value ≥