Determination of 50% endpoint titer using a simple formula

被引：15

作者：

Muthannan Andavar Ramakrishnan ^{[1
]}

机构：

[1] Division of Virology,Indian Veterinary Research Institute

来源：

World Journal of Virology | 2016年 / 02期

关键词：

Endpoint dilution; TCID50; Spearman-Karber; Reed and Muench;

D O I：

暂无

中图分类号：

O212 [数理统计];

学科分类号：

020208 ; 070103 ; 0714 ;

摘要：

Two commonly used methods for calculating 50% endpoint using serial dilutions are Spearman-Karber method and Reed and Muench method. To understand/apply the above formulas, moderate statistical/mathematical skills are necessary. In this paper, a simple formula/method for calculating 50% endpoints has been proposed. The formula yields essentially similar results as those of the SpearmanKarber method. The formula has been rigorously evaluated with several samples.

引用

页码：85 / 86

页数：2