Expression of B7-1 and B7-2 mediated by adenovirus enhanced T cell anti-hepatoma immunity

被引：0

作者：

Hongtian Huang Xiaoning Wang Qijun Qian Feng Shen Tianpei Xian Lehua Shi Han Chen Mengchao Wu Yajun GuoTumor Immunology and Gene Therapy Center Eastern Institute of Hepatobiiary Surgery Shanghai ^{[200433
]}

机构：

来源：

实验血液学杂志 | 1997年 / 03期

关键词：

cell; Expression of B7-1 and B7-2 mediated by adenovirus enhanced T cell anti-hepatoma immunity;

D O I：

暂无

中图分类号：

R730.3 [肿瘤免疫学与血清学];

学科分类号：

100214 ;

摘要：

<正> The ultimate aim of cancer immunotherapy is theinduction of tumor-specific T-lymphocyte responseseffective in eradicating disseminated tumors. There aregenerally tumor infiltrating T lymphocytes in situ oftumor, but most of which are inactive, one of the majorreasons of such Inactivation is that T lymphocytes areexposured to an antigen-specific TCR signal in theabsence of antigen-nonspecific or co-stimulatory signal.The co-stimulatory factors, B7-l and B7-2 on the surfaceof antigen presenting cells provide a key signal for thegeneration of T cell immunity. Sincc hepatoma usually

引用

页码：311 / 311

页数：1