RETREATMENT WITH FLUDARABINE AND CYCLOSPORINE FOR ONE CASE OF REFRACTORY PURE RED CELL APLASIA

被引:3
作者
Guangsheng HeXiang ZhangDepei WuAining SunMiao MiaoXiuli Wangand Zhengming Jin Department of Clinical HematologyKey Laboratory of Thrombosis and Hemostasis of Ministry of HealthJiangsu Insititute of Hematologythe First Affiliated Hospitalof Soochow UniversitySuzhou [215006 ]
机构
关键词
pure red cell aplasia; refractory; fludarabine;
D O I
暂无
中图分类号
R556 [贫血病];
学科分类号
1002 ; 100201 ;
摘要
<正>MANY cases of pure red cell aplasia(PRCA)were mediated by over-function of immune cells,and responded well to immunosuppressive therapy.1 Sometimes refractory cases also arose.Fludarabine is an analogue of adenosine resistant to deamination which is widely used for B-chronic lymphocytic leukemia(CLL)and other hematological malignancies.2 As a strong immunosuppressive agent,
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页码:60 / 62
页数:3
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[1]  
Fludarabine, cyclophosphamide and antithy- mocyte globulin for alternative donor transplants in acquired severe aplastic anemia: a report from the EBMT-SAA Working Party. Bacigalupo A,Locatelli F,Lanino E, et al. Bone Marrow Transplantation . 2005