Clinical Investigation of Radiation Retinopathy Fundus and Fluorescein Angiographic Features

<正> Purpose: To investigate the fundus and fluorescein angiographic features in the patients with radiation retinopathy.Clinical Materials: Color fundus photography and/or fluorescein angiography from 13 patients with nasopharyngeal carcinomas received external beam radiation were retrospectively analyzed.Results: In this study, 26 damaged eyes of 13 patients developed some .degree of radiation retinopathy. The earliest and most common finding was macular microvascular changes (microaneurysms and/or telangiectasia), which was observed in 100% (26 / 26) of the eyes. Intraretinal hemorrhages, macular capillary nonperfusion, and macular edema were noted in 84% , 50% , and 42% of the eyes, respectively. Conclusions: Radiation retinopathy is common after external beam radiation of nasopharyngeal carcinomas. The prominent changes include macular microvascular changes, intraretinal hemorrhages and macular capillary nonperfusion. Eye Science 1999; 15: 183 - 186.