The nucleocapsid of vesicular stomatitis virus

被引：0

作者：

LUO Ming Department of Microbiology the University of Alabama at Birmingham Birmingham USA ^{[35294
]}

机构：

来源：

ScienceChina(LifeSciences) | 2012年 / 55卷 / 04期

关键词：

RNA cavity; cross-molecular interactions; RNA access; phosphoprotein binding to the nucleocapsid; bullet-shaped virion;

D O I：

暂无

中图分类号：

Q939.4 [病毒（滤过性病毒）];

学科分类号：

071005 ; 100705 ;

摘要：

The nucleocapsid of vesicular stomatitis virus serves as the genomic template for transcription and replication. The viral genomic RNA is sequestered in the nucleocapsid in every step of the virus replication cycle. The structure of the nucleocapsid and the entire virion revealed how the viral genomic RNA is encapsidated and packaged in the virus. A unique mechanism for viral RNA synthesis is derived from the structure of the nuleocapsid and its interactions with the viral RNA-dependent RNA polymerase.

引用

页码：291 / 300

页数：10

共 7 条

[1]

Solution Structure of the C-Terminal Nucleoprotein–RNA Binding Domain of the Vesicular Stomatitis Virus Phosphoprotein[J] . Euripedes A. Ribeiro,Adrien Favier,Francine C.A. Gerard,Cédric Leyrat,Bernhard Brutscher,Danielle Blondel,Rob W.H. Ruigrok,Martin Blackledge,Marc Jamin.Journal of Molecular Biology . 2008 (2)

[2] Unconventional mechanism of mRNA capping by the RNA-dependent RNA polymerase of vesicular stomatitis virus [J].