Synthesis and biological evaluation of novel 1,2,4-triazole containing 1,2,3-thiadiazole derivatives

被引：9

作者：

YueDong Li ^{[1
]}

WuTao Mao ^{[1
]}

ZhiJin Fan ^{[1
]}

JuanJuan Li ^{[1
]}

Zhen Fang ^{[1
]}

XiaoTian Ji ^{[1
]}

XueWen Hua ^{[1
]}

GuangNing Zong ^{[1
]}

FengYun Li ^{[1
]}

ChaoLun Liu ^{[1
]}

JianHua Yu ^{[2
]}

机构：

[1] State Key Laboratory of Elemento-Organic Chemistry,Nankai University

[2] Division of Hematology,College of Medicine and School of Public Health,The Ohio State University

来源：

ChineseChemicalLetters | 2013年 / 24卷 / 12期

关键词：

1,2,3-Thiadiazole; 1,2,4-Triazole; Insecticidal activity; Anti-TMV activity;

D O I：

暂无

中图分类号：

O621.3 [有机合成化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of novel 1,2,4-triazoles containing 1,2,3-thiadiazole derivatives were designed and synthesized.Their structures were confrmed by melting points,IR,1H NMR,and elemental analysis and ESI-MS or HRMS.Preliminary bioassays indicated that these compounds exhibited very good insecticidal activity against Aphis laburni at 100 mg/mL,with mortality no less than 95%.Compounds 6a,6c,6f,6l showed higher curative activity against TMV and compound 6h showed a higher induction effects against TMV in vivo at 100 mg/mL.Collectively,our data demonstrate a new strategy for control of insects and viruses.

引用

页码：1134 / 1136

页数：3

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