Synthesis,insecticidal and acaricidal activities of novel 2-arylpyrroles

被引：0

作者：

LIU AiPing ^{[1
,2
]}

TANG Ming ^{[1
,3
]}

YU ShuYing ^{[1
,2
]}

LIU XingPing ^{[1
,2
]}

WANG XiaoGuang ^{[1
,2
]}

PEI Hui ^{[1
,2
]}

WU DaoXin ^{[1
,3
]}

HU Li ^{[1
,2
]}

OU XiaoMing ^{[1
,2
]}

HUANG MingZhi ^{[1
,2
]}

机构：

[1] National Engineering Research Center for Agrochemicals,Hunan Research Institute of Chemical Industry

[2] Hunan Province Key Laboratory for Agrochemicals

[3] School of Chemistry and Biological Engineering,Changsha University of Science and Technology

来源：

Science China(Chemistry) | 2013年 / 01期

关键词：

2-arylpyrroles; Chlorfenapyr; synthesis; insecticidal activity; acaricidal activity;

D O I：

暂无

中图分类号：

TQ450.2 [生物活性测定与安全性评价];

学科分类号：

090403 ;

摘要：

To search for novel 2-arylpyrroles with unique biological activities,a series of novel 2-arylpyrrole derivatives were designed and synthesized,and their structures were characterized by 1 H and 13 C NMR spectroscopy,MS spectrometry,and elemental analysis.Their insecticidal activities against Lepidopteran pests (e.g.Mythimna separata) and acaricidal activities against mites (e.g.Tetranychus urticae) were evaluated.The results of bioassays indicate that some of these title compounds exhibited excellent insecticidal and acaricidal activities.For example,4-bromo-1-((chloromethoxy)methyl)-2-(4-chloro phenyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile (6a),4-bromo-2-(4-chlorophenyl)-1-((2-fluoroethoxy)-methyl)-5-(trifluoromethyl)pyrrole-3-carbonitrile (6d) showed insecticidal activity against Mythimna separata and 4-bromo-2-(4-chlorophenyl)1-((isopropoxymethoxy)methyl)-5-(trifluoro methyl)pyrrole-3-carbonitrile (7d) showed acaricidal activity against Tetranychus urticae.They were more effective than Chlorfenapyr,which has been the only commercialized member of a new class of chemicals of 2-arylpyrroles.

引用

页码：117 / 123

页数：7

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