Synthesis of 2-(Benzodioxol-2-yl)acetic Acids as PPARδ Agonists

被引:0
作者
Jian Lei KANG1
机构
关键词
PPARδ; agonists; 2-(benzodioxol-2-yl)acetic acids; synthesis;
D O I
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中图分类号
O621.3 [有机合成化学];
学科分类号
070303 ; 081704 ;
摘要
A new series of compounds, 2-(benzodioxol-2-yl)acetic acids, have been synthesized. Their structures were confirmed by MS and 1H-NMR. The preliminary pharmacological screening showed that these compounds exhibited potent human PPARδ agonist activities.
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页码:1013 / 1016
页数:4
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