Effect of gastrin on protein kinase C and its subtype in human colon cancer cell line SW480

被引:0
|
作者
Bin Xie~1 Shuang Wu He~1 Xiao Dong Wang~2 1 Department of General Surgery
机构
关键词
gastrin; protein kinase C; colon neoplasms; cell line;
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中图分类号
R735.3 [肠肿瘤];
学科分类号
100214 ;
摘要
INTRODUCTIONGastrin is atrophic gastrointestinal hormone whichis secreted by G cell.Gastrin has long beenconsidered a growth stimulatory hormone formucosa of the gastrointestinal tract.The growthresponses of certain colorectal cancer cells,andxenografts,can be stimulated by endogenousgastrin.Protein kinase C (PKC) is a family ofisozymes that plays a crucial role in transducingsignals of many hormones,growth peptides,
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页码:304 / 306
页数:3
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