Synthesis and Crystal Structure of Chiral Spiro{1-bromo-4-hydroxy-5-N-cyclohexyl-butyrolactam-6-oxo-dirings[3.1.0]hexane-2,3′-(4′-diphenylcarbinol-5′-menthyloxy-butyrolatone)}

被引：1

作者：

王建革 ^{[1
]}

秦建华 ^{[1
]}

王建平 ^{[1
]}

李英飞 ^{[2
]}

李华民 ^{[3
]}

机构：

[1] College of Chemistry and Chemical Engineering,Luoyang Normal University

[2] Chemical Engineering & Pharmaceutics College,Henan University of Science and Technology 3. College of Chemistry,Beijing Normal University

来源：

结构化学 | 2008年 / 10期

关键词：

symmetric synthesis; butyrolactam; spiro/cyclopropane; crystal structure;

D O I：

10.14102/j.cnki.0254-5861.2008.10.009

中图分类号：

O626.3 [含单异原子的六节杂环];

学科分类号：

070303 ; 081704 ;

摘要：

A novel compound of chiral spiro{1-bromo-4-hydroxy-5-N-cyclohexyl-butyro-lactam-6-oxo-dirings3.1.0hexane-2,3′-(4′-diphenylcarbinol-5′-menthyloxy-butyrolatone)} was synthesized via tandem nucleophilic substitution reaction under mild conditions=and its structure was determined by IR =1H NMR=elemental analysis and X-ray diffraction.The crystal structure of this compound is of monoclinic system=space group P21 with a=9.7356(9)=b=12.2760(12)=c=14.9577(14)=β=101.0300(10)°=Mr=680.66=Z=2=V=1754.6(3)3=Dc=1.288 g/cm3=μ(MoKα)=1.216 mm-1=F(000)=716=the final R=0.0434 and wR=0.0996.

引用

页码：1265 / 1269

页数：5