Etiology for Degenerative Disc Disease

被引:13
|
作者
Dhungana Hemanta [1 ]
Xiao-xing Jiang [1 ]
Zhen-zhou Feng [1 ]
Zi-xian Chen [1 ]
Yuan-wu Cao [1 ]
机构
[1] Department of Orthopedics,Zhongshan Hospital,Fudan University
关键词
degenerative intervertebral disc disease; cervical spine; genetics; back pain;
D O I
暂无
中图分类号
R681.5 [脊柱及背疾病];
学科分类号
1002 ; 100210 ;
摘要
Degenerative disc disease is a multifaceted progressive irreversible condition and an inevitable part of aging,which has been found to be a contributing factor for low back pain and might cause radiculopathy,myelopathy,spinal stenosis,degenerative spondylolisthesis,and herniations.Its etiology is complex and multifactorial.Although genetics influence more dominant,the occupational and mechanical influences still persist as a major risk factor.This review emphasizes up-to-date knowledge regarding etiology of disc degeneration with special consideration on occupational,lifestyle factors,and genetic polymorphisms.
引用
收藏
页码:185 / 191
页数:7
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