Controlled Release of the Indomethacin Microencapsulation Based on Layer-by-layer Assembly by Polyelectrolyte Multilayers

被引：0
|
作者：
CHEN You-fang
机构：
来源：
ChineseJournalofBiomedicalEngineering | 2007年 / 01期
关键词：
Indomethacin; Encapsulated; Controlled release; Self-assembly; Polyelectrolyte;
D O I：
暂无
中图分类号：
R944 [剂型];
学科分类号：
摘要：
Indomethacin has been encapsulated with polyelectrolyte multilayers for controlled release. Gelatin and alginate were alternatively deposited on indomethacin microcrystals. The released amount of indomethacin from coated microcrystals in pH6.8 phosphate buffer solution (PBS) was measured with a UV spectrophometer. The polyelectrolyte multilayer capsule thickness was proved to control the release rate. The effects of osmotic pressure existed during the release process of indomethacin from microcapsules coated by (gelatin/alginate).
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页码：8 / 13
页数：6
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