Mucosa-associated lymphoid tissue lymphoma of the transverse colon: A case report

We herein present a case of a 75-year-old female with mucosa-associated lymphoid tissue (MALT) lymphoma of the transverse colon with the stage IE (Ann Arbor clas- sifi cation). Colonoscopy revealed the tumor’s appearance as a IIa plus ?Research Society for Cancer of Colon, Rectum and Anus, measuring less than 2 cm in diameter. Histologically, the tumor was diagnosed as MALT lymphoma because of the presence of lymphoepithelial lesions consisting of diffuse proliferation of atypical lymphocytes and glandular de- struction. The majority of these lymphocytes immunohis- tochemically stained for the B-lymphocyte marker. The patient fi rst underwent H pylori eradication therapy withLansap?. However, the tumor size gradually increased over the next 4 mo and the patient eventually underwent surgical resection. The operative procedure included a partial colectomy with dissection of the paracolic lymph nodes. The tumor measured 45 mm x 30 mm in diam- eter and histological examination showed that the lym- phoma cells had infi ltrated the muscle layer of the colon without nodal involvement. The patient has had no re- currence postoperatively without any chemotherapy.