Regioselective Synthesis and Base Catalyzed Transacylation of Substituted 1H-Pyrazole-4-carboxamides

被引：0
|
作者：
任军
张晓弘
刘莹
陈卫强
金桂玉
机构：
来源：
ChineseJournalofChemistry | 2002年 / 01期
关键词：
regioselectivity; 1H-pyrazole-4-carboxamide; transacylation; fungicidal activity;
D O I：
暂无
中图分类号：
O643.3 [催化];
学科分类号：
081705 ;
摘要：
New type of substituted 1H-pyrazole-4-carboxamides were obtained by regioselective synthesis under the catalysis of different bases. The structures of the title compounds were confirmed by elemental analysis, 1H NMR, IR, MS and X-ray crystallography. Compounds 1 were transacylated into their corresponding amides 3 in the presence of sodium hydride. Preliminary bioassays indicated that some compounds showed fungicidal activities against Rhizoctonia solani and Sclerotinia sclerotiorum.
引用
收藏
页码：96 / 102 +1
页数：8
相关论文
共 50 条
  • [1] Regioselective synthesis and base catalyzed transacylation of substituted 1H-pyrazole-4-carboxamides
    Ren, J
    Zhang, XH
    Liu, Y
    Chen, WQ
    Jin, GY
    CHINESE JOURNAL OF CHEMISTRY, 2002, 20 (01) : 96 - 102
  • [2] Synthesis of pyrazole-4-carboxamides as potential fungicide candidates
    Cuntao Dong
    Wei Gao
    Xiaotian Li
    Susu Sun
    Jingqian Huo
    Yanen Wang
    Da Ren
    Jinlin Zhang
    Lai Chen
    Molecular Diversity, 2021, 25 : 2379 - 2388
  • [3] Synthesis of pyrazole-4-carboxamides as potential fungicide candidates
    Dong, Cuntao
    Gao, Wei
    Li, Xiaotian
    Sun, Susu
    Huo, Jingqian
    Wang, Yanen
    Ren, Da
    Zhang, Jinlin
    Chen, Lai
    MOLECULAR DIVERSITY, 2021, 25 (04) : 2379 - 2388
  • [4] Synthesis and Biological Study of Novel N-(1H-Pyrazol-4-yl)-1H-pyrazole-3(5)-carboxamides
    Zhang, Daqiang
    Xu, Gaofei
    Liu, Yanhong
    Wang, Daoquan
    Yang, Xinling
    Yuan, Dekai
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2015, 35 (10) : 2191 - 2198
  • [5] Rhodium(III)-Catalyzed Regioselective C-H Activation/Annulation for the Diverse Pyrazole-Core Substituted Furans
    Cai, Hongyun
    Thombal, Raju S.
    Li, Xin
    Lee, Yong Rok
    ADVANCED SYNTHESIS & CATALYSIS, 2019, 361 (17) : 4022 - 4032
  • [6] Indium trichloride catalyzed regioselective synthesis of substituted pyrroles in water
    Suresh, Rajendran
    Muthusubramanian, Shanmugam
    Nagaraj, Muthupandi
    Manickam, Govindaswamy
    TETRAHEDRON LETTERS, 2013, 54 (14) : 1779 - 1784
  • [7] Silver-catalyzed Regioselective Synthesis of N-aryl-1H-pyrazolyl-substituted Benzenesulfonamides from Ynamides and Pyrazoles
    Karunakar, Galla V.
    Raju, Chittala Emmaniel
    Himaja, Karra Sai Bhavani Nagasri
    Kumar, Perla Bharath
    Sridhar, Balasubramanian
    CHEMISTRY-AN ASIAN JOURNAL, 2023, 18 (15)
  • [8] Synthesis, antifungal activity and in vitro mechanism of novel 1-substituted-5-trifluoromethyl-1H-pyrazole-4-carboxamide derivatives
    Yang, Jingxin
    Xie, Dewen
    Zhang, Chengzhi
    Zhao, Cailong
    Wu, Zhibing
    Xue, Wei
    ARABIAN JOURNAL OF CHEMISTRY, 2022, 15 (08)
  • [9] Regioselective synthesis of cytotoxic 4-(1-alkynyl)-substituted 2-(5H)-furanones
    Bellina, F
    Falchi, E
    Rossi, R
    TETRAHEDRON, 2003, 59 (46) : 9091 - 9100
  • [10] Design, Synthesis and Biological Activity of Pyrazole-4-carboxamides Compounds Containing 1,2,4,5-Tetrasubstituted Phenyl
    Dong, Xinrui
    Xia, Zhe
    Wang, Zhenxue
    Bian, Qiang
    Li, Huabin
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2020, 41 (12): : 2759 - 2765
12345