Cell therapy for macular degeneration—first phase Ⅰ/Ⅱ pluripotent stem cell-based clinical trial shows promise

被引:0
|
作者
CHEN ZhiGuo [1 ,2 ]
ZHANG Y.Alex [1 ,2 ]
机构
[1] Cell Therapy Center,Xuanwu Hospital,Capital Medical University and Key Laboratory of Neurodegeneration,Ministry of Education
[2] Center of Neural Injury and Repair,Beijing Institute for Brain Disorders
关键词
stem; cell; Cell therapy for macular degeneration; first phase; pluripotent stem cell-based clinical trial shows promise; PSCs;
D O I
暂无
中图分类号
R774.5 [黄斑、中心窝疾病];
学科分类号
100212 ;
摘要
Embryonic stem(ES)cells,a type of pluripotent stem cells(PSCs)that are derived from the inner cell mass of blastocysts,have been discovered for more than three decades[1].Given the almost infinite self-renewal capacity and the potential to differentiate into any specific cell type in an individual,ES cells and PSCs have brought hope for the treatment of many unmet diseases.However,the advantages of PSCs—the highly proliferative and plastic capacities,also give rise to concerns regarding the development of tumors
引用
收藏
页码:119 / 120
页数:2
相关论文
共 50 条
  • [1] Cell therapy for macular degeneration—first phase Ⅰ/Ⅱ pluripotent stem cell-based clinical trial shows promise
    CHEN ZhiGuo
    ZHANG YAlex
    Science China(Life Sciences), 2015, 58 (01) : 119 - 120
  • [2] Cell therapy for macular degeneration—first phase I/II pluripotent stem cell-based clinical trial shows promise
    ZhiGuo Chen
    Y. Alex Zhang
    Science China Life Sciences, 2015, 58 : 119 - 120
  • [3] Cell therapy for macular degeneration-first phase I/II pluripotent stem cell-based clinical trial shows promise
    Chen ZhiGuo
    Zhang, Y. Alex
    SCIENCE CHINA-LIFE SCIENCES, 2015, 58 (01) : 119 - 120
  • [4] Pluripotent Stem Cell-Based Cell Therapy- Promise and Challenges
    Yamanaka, Shinya
    CELL STEM CELL, 2020, 27 (04) : 523 - 531
  • [5] Induced pluripotent stem cell-based therapy for age-related macular degeneration
    Bracha, Peter
    Moore, Nicholas A.
    Ciulla, Thomas A.
    EXPERT OPINION ON BIOLOGICAL THERAPY, 2017, 17 (09) : 1113 - 1126
  • [6] Pluripotent Stem Cell-Based Cancer Therapy: Promise and Challenges
    Sharkis, Saul J.
    Jones, Richard J.
    Civin, Curt
    Jang, Yoon-Young
    SCIENCE TRANSLATIONAL MEDICINE, 2012, 4 (127)
  • [7] Photoreceptor cell replacement in macular degeneration and retinitis pigmentosa: A pluripotent stem cell-based approach
    Gagliardi, Giuliana
    Ben M'Barek, Karim
    Goureau, Olivier
    PROGRESS IN RETINAL AND EYE RESEARCH, 2019, 71 : 1 - 25
  • [8] First human clinical trial of embryonic stem cell-based therapy
    不详
    MOLECULAR THERAPY, 2009, 17 (03) : 401 - 401
  • [9] Strategies of pluripotent stem cell-based therapy for retinal degeneration: update and challenges
    Maeda, Tadao
    Mandai, Michiko
    Sugita, Sunao
    Kime, Cody
    Takahashi, Masayo
    TRENDS IN MOLECULAR MEDICINE, 2022, 28 (05) : 388 - 404
  • [10] The prospect of pluripotent stem cell-based therapy
    Borisenko G.G.
    Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 2009, 3 (3) : 248 - 258